Chlorthalidone and Prochlorperazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Chlorthalidone (chlorthalidone) and Prochlorperazine (prochlorperazine). Common drug interactions include nephrogenic anaemia among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Chlorthalidone and Prochlorperazine. It is created by eHealthMe based on reports of 62 people who take the same drugs from the FDA, and is updated regularly.

What is Chlorthalidone?

Chlorthalidone has active ingredients of chlorthalidone. It is often used in high blood pressure. eHealthMe is studying from 12,482 Chlorthalidone users. Check the latest studies of Chlorthalidone.

What is Prochlorperazine?

Prochlorperazine has active ingredients of prochlorperazine. It is often used in nausea. eHealthMe is studying from 14,632 Prochlorperazine users. Check the latest studies of Prochlorperazine.

On Jul, 19, 2026

62 people who take Chlorthalidone and Prochlorperazine together, and have interactions are studied.

Chlorthalidone and Prochlorperazine drug interactions.

What are the common drug interactions of Chlorthalidone and Prochlorperazine, by gender? *:

female:

Nephrogenic anaemia (anaemia due to kidney disease)
Pain
Plasma cell myeloma (cancer that begins in plasma cells)
Post procedural complication
Procedural pain
Pruritus (severe itching of the skin)
Pulseless electrical activity
Renal failure (kidney dysfunction)
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Respiratory distress (difficulty in breathing)

male:

Fatigue (feeling of tiredness)
Asthenia (weakness)
Muscle spasms (muscle contraction)
Pain in extremity
Palpitations (feelings or sensations that your heart is pounding or racing)
Peripheral swelling
Productive cough
Pruritus (severe itching of the skin)
Rash macular (small, flat red spots)
Skin fissures (a crack in the skin)

What are the common drug interactions of Chlorthalidone and Prochlorperazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Decreased appetite
Diarrhoea

50-59:

Fatigue (feeling of tiredness)
Muscle spasms (muscle contraction)
Arthralgia (joint pain)
Asthenia (weakness)
Constipation
Cough
Dehydration (dryness resulting from the removal of water)
Dry skin
Gait disturbance
Hyperhidrosis (abnormally increased sweating)

60+:

Death
Pyrexia (fever)
Chills (felling of cold)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Decreased appetite
Dehydration (dryness resulting from the removal of water)
Disease progression
Drug ineffective
Dysphonia (speech disorder attributable to a disorder of phonation)
Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 10 people, 16.13%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 7 people, 11.29%
High Blood Cholesterol: 6 people, 9.68%
Renal Disorder (kidney disease): 5 people, 8.06%
Dry Skin: 5 people, 8.06%
Renal Cell Carcinoma (a kidney cancer): 4 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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