Cinnamon and Actos drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cinnamon (cassia cinnamon) and Actos (pioglitazone hydrochloride). Common drug interactions include haemoglobin decreased among females and dieulafoy's vascular malformation among males.

The phase IV clinical study analyzes what interactions people have when they take Cinnamon and Actos. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.

What is Cinnamon?

Cinnamon has active ingredients of cassia cinnamon. It is often used in diabetes. eHealthMe is studying from 4,110 Cinnamon users. Check the latest studies of Cinnamon.

What is Actos?

Actos has active ingredients of pioglitazone hydrochloride. It is often used in diabetes. eHealthMe is studying from 49,754 Actos users. Check the latest studies of Actos.

On Jul, 12, 2026

51 people who take Cinnamon and Actos together, and have interactions are studied.

What are the common drug interactions of Cinnamon and Actos, by gender? *:

female:

Haemoglobin decreased
Heart rate increased
Incisional drainage
Jaw fracture
Malignant neoplasm progression (cancer tumour came back)
Pancreatic mass
Pancreatic neuroendocrine tumour
Pancreatitis (inflammation of pancreas)
Perineal abscess
Perirectal abscess

male:

Dieulafoy's vascular malformation (dieulafoy's vascular malformation may cause severe, potentially life-threatening gastro-intestinal bleeding)
Gastritis (inflammation of stomach)
Drug effect decreased
Asthma
Blindness
Blood glucose decreased
Counterfeit drug administered
Death
Dysgeusia (disorder of the sense of taste)
Fatigue (feeling of tiredness)

What are the common drug interactions of Cinnamon and Actos, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Psoriasis (immune-mediated disease that affects the skin)
Renal tubular necrosis (death of kidney tubules)
Abdominal distension
Blood glucose decreased
Blood thyroid stimulating hormone decreased
Blood thyroid stimulating hormone increased
Chronic kidney disease
Dizziness
Drug effect decreased
Dyspnoea (difficult or laboured respiration)

50-59:

Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Back pain
Pancreatic neuroendocrine tumour
Rosacea (a skin condition that causes facial redness)
Upper respiratory tract infection
Abdominal discomfort
Disturbance in attention
Headache (pain in head)
Hypoaesthesia (reduced sense of touch or sensation)

60+:

Pneumonia
Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Diabetes mellitus inadequate control
Fatigue (feeling of tiredness)
Haemorrhagic anaemia (anaemia due to excessive bleeding)
Headache (pain in head)
Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
Herpes zoster
Lower respiratory tract infection
Memory impairment

What are the existing conditions these people have? *

Pain: 6 people, 11.76%
High Blood Cholesterol: 6 people, 11.76%
Type 2 Diabetes: 5 people, 9.80%
Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 5 people, 9.80%
High Blood Pressure: 5 people, 9.80%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 7.84%
Blood Pressure Abnormal: 4 people, 7.84%
Asthma: 4 people, 7.84%
Neuropathy Peripheral (surface nerve damage): 3 people, 5.88%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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