Cinnamon and Digoxin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cinnamon (cassia cinnamon) and Digoxin (digoxin). Common drug interactions include arthritis among females and interstitial lung disease among males.

The phase IV clinical study analyzes what interactions people have when they take Cinnamon and Digoxin. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Cinnamon?

Cinnamon has active ingredients of cassia cinnamon. It is often used in diabetes. eHealthMe is studying from 4,110 Cinnamon users. Check the latest studies of Cinnamon.

What is Digoxin?

Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.



On Jul, 15, 2026

44 people who take Cinnamon and Digoxin together, and have interactions are studied.

Cinnamon and Digoxin drug interactions.

What are the common drug interactions of Cinnamon and Digoxin, by gender? *:

female:

  1. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  2. Atrophic vulvovaginitis (inflammation of the vulva)
  3. Breast cancer
  4. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  5. Burning sensation
  6. Cataract (clouding of the lens inside the eye)
  7. Chest pain
  8. Constipation
  9. Cystocele (a condition that occurs when the tough fibrous wall between a woman's bladder and her vagina is torn by childbirth)
  10. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

male:

  1. Interstitial lung disease
  2. Pneumonia
  3. Fatigue (feeling of tiredness)
  4. Headache (pain in head)
  5. Pain
  6. Drug ineffective
  7. Blood glucose decreased
  8. Choking (mechanical obstruction of the flow of air from the environment into the lungs)
  9. Cough
  10. Death

What are the common drug interactions of Cinnamon and Digoxin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  2. Dizziness
  3. Influenza
  4. Lethargy (tiredness)
  5. Muscular weakness (muscle weakness)
  6. Rhinorrhoea (watery mucus discharge from the nose)
  7. Sluggishness (lacking alertness)
  8. Stupor (lack of critical cognitive function and level of consciousness)

50-59:

  1. Nausea (feeling of having an urge to vomit)
  2. Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
  3. Optic nerve infarction (optic nerve fibre damage)
  4. Optic nerve injury
  5. Optic neuropathy (optic nerve damage)
  6. Pain
  7. Sepsis (a severe blood infection that can lead to organ failure and death)
  8. Somnolence (a state of near-sleep, a strong desire for sleep)
  9. Abnormal dreams
  10. Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)

60+:

  1. Constipation
  2. Interstitial lung disease
  3. Dyspnoea (difficult or laboured respiration)
  4. Fatigue (feeling of tiredness)
  5. Headache (pain in head)
  6. Infection
  7. Injury
  8. Blood glucose decreased
  9. Choking (mechanical obstruction of the flow of air from the environment into the lungs)
  10. Death

What are the existing conditions these people have? *

  1. High Blood Cholesterol: 7 people, 15.91%
  2. Pain: 6 people, 13.64%
  3. High Blood Pressure: 6 people, 13.64%
  4. Cardiac Disorder: 6 people, 13.64%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 11.36%
  6. Prostate Cancer: 3 people, 6.82%
  7. Blood Pressure Abnormal: 3 people, 6.82%

* Approximation only. Some reports may have incomplete information.

Do you take Cinnamon and Digoxin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cinnamon and Digoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cinnamon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Digoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cinnamon and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Digoxin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on cassia cinnamon and digoxin (the active ingredients of Cinnamon and Digoxin, respectively), and Cinnamon and Digoxin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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