Cipro and Buscopan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cipro (ciprofloxacin hydrochloride) and Buscopan (hyoscine butylbromide). Common drug interactions include progressive multifocal leukoencephalopathy among females and abdominal discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Cipro and Buscopan. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Cipro?

Cipro has active ingredients of ciprofloxacin hydrochloride. It is often used in urinary tract infection. eHealthMe is studying from 35,126 Cipro users. Check the latest studies of Cipro.

What is Buscopan?

Buscopan has active ingredients of hyoscine butylbromide. eHealthMe is studying from 4,828 Buscopan users. Check the latest studies of Buscopan.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

16 people who take Cipro and Buscopan together, and have interactions are studied.

What are the common drug interactions of Cipro and Buscopan, by gender? *:

female:

Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Drug ineffective
Pyrexia (fever)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Lymphopenia (an abnormally low level of lymphocytes in the blood)
Nausea (feeling of having an urge to vomit)
Optic neuritis (optic nerve inflammation)
Pain in extremity

male:

Abdominal discomfort
Colitis (inflammation of colon)
Abdominal pain lower
Agitation (state of anxiety or nervous excitement)
Bladder obstruction
Blood creatinine increased
Chills (felling of cold)
Constipation
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)

What are the common drug interactions of Cipro and Buscopan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Renal neoplasm (kidney tumour)

10-19:

n/a

20-29:

n/a

30-39:

Pneumonia

40-49:

n/a

50-59:

Abdominal pain
Blood creatinine increased
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Drug ineffective
Fatigue (feeling of tiredness)
Frequent bowel movements
Inflammatory bowel disease
Pain in extremity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

60+:

Abdominal discomfort
Colitis (inflammation of colon)
Abdominal pain lower
Agitation (state of anxiety or nervous excitement)
Bladder obstruction
Chills (felling of cold)
Constipation
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Drug administration error
Fall

What are the existing conditions these people have? *

Pain: 3 people, 18.75%
Abdominal Discomfort: 3 people, 18.75%
Multiple Myeloma (cancer of the plasma cells): 2 people, 12.50%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 12.50%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 6.25%
Type 2 Diabetes: 1 person, 6.25%
Sepsis (a severe blood infection that can lead to organ failure and death): 1 person, 6.25%
Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 6.25%
Ovarian Cancer (cancer of ovary): 1 person, 6.25%
High Blood Cholesterol: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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