Cipro and Gilenya drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Cipro (ciprofloxacin hydrochloride) and Gilenya (fingolimod). Common drug interactions include memory impairment among females and gait disturbance among males.
The phase IV clinical study analyzes what interactions people have when they take Cipro and Gilenya. It is created by eHealthMe based on reports of 78 people who take the same drugs from the FDA, and is updated regularly.
What is Cipro?
Cipro has active ingredients of ciprofloxacin hydrochloride. It is often used in urinary tract infection. eHealthMe is studying from 35,126 Cipro users. Check the latest studies of Cipro.
What is Gilenya?
Gilenya has active ingredients of fingolimod. It is often used in multiple sclerosis. eHealthMe is studying from 111,893 Gilenya users. Check the latest studies of Gilenya.
78 people who take Cipro and Gilenya together, and have interactions are studied.

What are the common drug interactions of Cipro and Gilenya, by gender? *:
female:
- Memory impairment
- Pyrexia (fever)
- White blood cell count increased
- Chest pain
- Blood pressure increased
- Dizziness
- Gait disturbance
- Micturition urgency (urgency to pass the urine)
- Visual impairment
- Back pain
male:
- Gait disturbance
- Loss of consciousness
- Muscular weakness (muscle weakness)
- Unresponsive to stimuli
- Activated partial thromboplastin time prolonged
- Alanine aminotransferase increased
- Anion gap decreased
- Anxiety
- Aphasia (damage to the parts of the brain that control language)
- Blood albumin decreased
What are the common drug interactions of Cipro and Gilenya, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Pyrexia (fever)
- Headache (pain in head)
- Arthralgia (joint pain)
- Back pain
- Alanine aminotransferase increased
- Aphasia (damage to the parts of the brain that control language)
- Bladder pain
- Blood thyroid stimulating hormone increased
- Burning sensation
- C-reactive protein increased
40-49:
- White blood cell count decreased
- Alanine aminotransferase increased
- Blood glucose increased
- Haematocrit decreased
- Haemoglobin decreased
- Lymphocyte count decreased
- Nausea (feeling of having an urge to vomit)
- Blood calcium decreased
- Blood creatine decreased
- Depression
50-59:
- Confusional state
- Dehydration (dryness resulting from the removal of water)
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
- Headache (pain in head)
- Loss of consciousness
- Pain
- Bradycardia (abnormally slow heart action)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Eye pain
- Micturition urgency (urgency to pass the urine)
60+:
- Gait disturbance
- Balance disorder
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Asthenia (weakness)
- Back pain
- Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
- Drug ineffective
- Joint swelling
- Lethargy (tiredness)
- Sinusitis (inflammation of sinus)
What are the existing conditions these people have? *
- Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 17 people, 21.79%
- Depression: 10 people, 12.82%
- Stress And Anxiety: 6 people, 7.69%
- Constipation: 5 people, 6.41%
- Pain: 4 people, 5.13%
- Insomnia (sleeplessness): 4 people, 5.13%
- Headache (pain in head): 4 people, 5.13%
- Diabetes: 4 people, 5.13%
* Approximation only. Some reports may have incomplete information.
Do you take Cipro and Gilenya?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Cipro and Gilenya:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cipro:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Gilenya:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cipro and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Gilenya and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Christopher KL, Elner VM, Demirci H, "Conjunctival Lymphoma in a Patient on Fingolimod for Relapsing-Remitting Multiple Sclerosis", Ophthalmic Plastic & Reconstructive Surgery, 2017 May .
- Alroughani R, "Fingolimod-associated amenorrhea: a report of three cases", Multiple Sclerosis Journal, 2014 Jan .
- Christopher, K. L., Elner, V. M., & Demirci, H. , "Conjunctival lymphoma in a patient on fingolimod for relapsing-remitting multiple sclerosis", Ophthalmic plastic and reconstructive surgery , 2014 Jan .
- Christopher KL, Elner VM, Demirci H, "Conjunctival Lymphoma in a Patient on Fingolimod for Relapsing-Remitting Multiple Sclerosis", Ophthalmic Plastic & Reconstructive Surgery, 2017 May .
- Alroughani R, "Fingolimod-associated amenorrhea: a report of three cases", Multiple Sclerosis Journal, 2014 Jan .
- Christopher, K. L., Elner, V. M., & Demirci, H. , "Conjunctival lymphoma in a patient on fingolimod for relapsing-remitting multiple sclerosis", Ophthalmic plastic and reconstructive surgery , 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on ciprofloxacin hydrochloride and fingolimod (the active ingredients of Cipro and Gilenya, respectively), and Cipro and Gilenya (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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