Cisplatin and Q10 drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Cisplatin (cisplatin) and Q10 (coenzyme q - 10). Common drug interactions include presyncope among females and malaise among males.
The phase IV clinical study analyzes what interactions people have when they take Cisplatin and Q10. It is created by eHealthMe based on reports of 31 people who take the same drugs from the FDA, and is updated regularly.
What is Cisplatin?
Cisplatin has active ingredients of cisplatin. It is often used in chemotherapy. eHealthMe is studying from 92,837 Cisplatin users. Check the latest studies of Cisplatin.
What is Q10?
Q10 has active ingredients of coenzyme q - 10. eHealthMe is studying from 34,259 Q10 users. Check the latest studies of Q10.
31 people who take Cisplatin and Q10 together, and have interactions are studied.

What are the common drug interactions of Cisplatin and Q10, by gender? *:
female:
- Presyncope
- Pyrexia (fever)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Hypokalaemia (low potassium)
- Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
- Hypotension (abnormally low blood pressure)
- Renal failure acute (rapid kidney dysfunction)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Thrombocytopenia (decrease of platelets in blood)
- Abdominal pain lower
male:
- Malaise (a feeling of general discomfort or uneasiness)
- Pneumonitis (inflammation of the walls of the alveoli in the lungs)
- Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
- Cardiac failure congestive
- Constipation
- Diarrhoea
- Mouth ulceration (mouth ulcers)
- Rash
- Bradyarrhythmia (heart slowness)
- Cardiac arrest
What are the common drug interactions of Cisplatin and Q10, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Malaise (a feeling of general discomfort or uneasiness)
- Pneumonitis (inflammation of the walls of the alveoli in the lungs)
- Abdominal pain lower
- Abdominal pain upper
- Dyspepsia (indigestion)
- Dyspnoea exertional (breathlessness or shortness of breath)
- Fatigue (feeling of tiredness)
- Gastrointestinal necrosis (destruction of gastrointestinal organ)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
60+:
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
- Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
- Hypotension (abnormally low blood pressure)
- Renal failure (kidney dysfunction)
- Renal failure acute (rapid kidney dysfunction)
- Renal tubular necrosis (death of kidney tubules)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Thrombocytopenia (decrease of platelets in blood)
- Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
What are the existing conditions these people have? *
- Constipation: 9 people, 29.03%
- Gastroesophageal Cancer: 7 people, 22.58%
- Nausea (feeling of having an urge to vomit): 6 people, 19.35%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 16.13%
- Thrombocytopenia (decrease of platelets in blood): 5 people, 16.13%
- Gastric Ulcer (stomach ulcer): 5 people, 16.13%
- Pain: 5 people, 16.13%
- Oesophageal Squamous Cell Carcinoma Metastatic (cancer that begins in flat cells lining the oesophagus spreads to other part): 5 people, 16.13%
- Gastritis (inflammation of stomach): 5 people, 16.13%
- Urinary Incontinence (inability to control the flow of urine and involuntary urination): 4 people, 12.90%
* Approximation only. Some reports may have incomplete information.
Do you take Cisplatin and Q10?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Cisplatin and Q10:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cisplatin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Q10:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cisplatin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Q10 and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Peel MM, Cooke M, Lewis-Peel HJ, Lea RA, Moyle W, "A randomized controlled trial of coenzyme Q 10 for fatigue in the late-onset sequelae of poliomyelitis", Complementary therapies in medicine, 2015 Dec .
- Schlumbrecht MP, Hehr K, "Cisplatin-induced bradycardia and the importance of the QT interval", Journal of Oncology Pharmacy Practice, 2015 Jan .
- Peel MM, Cooke M, Lewis-Peel HJ, Lea RA, Moyle W, "A randomized controlled trial of coenzyme Q 10 for fatigue in the late-onset sequelae of poliomyelitis", Complementary therapies in medicine, 2015 Dec .
- Schlumbrecht MP, Hehr K, "Cisplatin-induced bradycardia and the importance of the QT interval", Journal of Oncology Pharmacy Practice, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on cisplatin and coenzyme q - 10 (the active ingredients of Cisplatin and Q10, respectively), and Cisplatin and Q10 (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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