Citalopram hydrobromide and Avalide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Citalopram hydrobromide (citalopram hydrobromide) and Avalide (hydrochlorothiazide; irbesartan). Common drug interactions include infection among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Citalopram hydrobromide and Avalide. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Citalopram hydrobromide?

Citalopram hydrobromide has active ingredients of citalopram hydrobromide. It is often used in depression. eHealthMe is studying from 36,878 Citalopram hydrobromide users. Check the latest studies of Citalopram hydrobromide.

What is Avalide?

Avalide has active ingredients of hydrochlorothiazide; irbesartan. It is often used in high blood pressure. eHealthMe is studying from 5,943 Avalide users. Check the latest studies of Avalide.



On Jul, 16, 2026

16 people who take Citalopram hydrobromide and Avalide together, and have interactions are studied.

Citalopram hydrobromide and Avalide drug interactions.

What are the common drug interactions of Citalopram Hydrobromide and Avalide, by gender? *:

female:

  1. Infection
  2. Drug ineffective
  3. Pain
  4. Weight decreased
  5. Tendon operation
  6. Chronic kidney disease
  7. Renal failure (kidney dysfunction)
  8. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  9. Headache (pain in head)
  10. Hypersensitivity

male:

  1. Diarrhoea
  2. Ascites (accumulation of fluid in the abdominal cavity)
  3. Upper respiratory tract infection
  4. Weight increased
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  7. Haematochezia (passage of stools containing blood)
  8. Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
  9. Liver disorder (liver diseases)
  10. Pancreatitis (inflammation of pancreas)

What are the common drug interactions of Citalopram Hydrobromide and Avalide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Infection
  2. Drug ineffective
  3. Pain
  4. Weight decreased
  5. Tendon operation
  6. Headache (pain in head)
  7. Hypersensitivity

30-39:

n/a

40-49:

  1. Ascites (accumulation of fluid in the abdominal cavity)
  2. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  3. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  4. Diarrhoea
  5. Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
  6. Liver disorder (liver diseases)
  7. Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
  8. Pancreatitis (inflammation of pancreas)
  9. Renal failure (kidney dysfunction)
  10. Swelling face

50-59:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  4. Cardiac failure congestive
  5. Bipolar disorder (mood disorder)
  6. Pancreatitis (inflammation of pancreas)

60+:

  1. Abdominal adhesions (inflammation of abdomen)
  2. Breast cancer
  3. Breast cancer recurrent
  4. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  5. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  6. Dizziness
  7. Dry mouth
  8. Haematochezia (passage of stools containing blood)
  9. Hyperkeratosis (thickening of the outer layer of the skin)
  10. Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

  1. Diabetes: 3 people, 18.75%
  2. Gastric Ph Decreased: 3 people, 18.75%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 12.50%
  4. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 12.50%
  5. Asthma: 2 people, 12.50%
  6. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 12.50%
  7. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 12.50%
  8. Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 12.50%
  9. Menopause (end of monthly cycles in women): 2 people, 12.50%
  10. Osteoporosis (bones weak and more likely to break): 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Citalopram hydrobromide and Avalide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Citalopram hydrobromide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Avalide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Citalopram hydrobromide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Avalide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on citalopram hydrobromide and hydrochlorothiazide; irbesartan (the active ingredients of Citalopram hydrobromide and Avalide, respectively), and Citalopram hydrobromide and Avalide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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