Clarithromycin and Estraderm drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clarithromycin (clarithromycin) and Estraderm (estradiol). Common drug interactions include sepsis among females.

The phase IV clinical study analyzes what interactions people have when they take Clarithromycin and Estraderm. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Clarithromycin?

Clarithromycin has active ingredients of clarithromycin. It is often used in sinusitis. eHealthMe is studying from 45,044 Clarithromycin users. Check the latest studies of Clarithromycin.

What is Estraderm?

Estraderm has active ingredients of estradiol. It is often used in hormone replacement therapy. eHealthMe is studying from 3,441 Estraderm users. Check the latest studies of Estraderm.

On Jul, 21, 2026

12 people who take Clarithromycin and Estraderm together, and have interactions are studied.

Clarithromycin and Estraderm drug interactions.

What are the common drug interactions of Clarithromycin and Estraderm, by gender? *:

female:

Sepsis (a severe blood infection that can lead to organ failure and death)
Headache (pain in head)
Pulmonary haemorrhage (acute bleeding from the lung)
White blood cell count decreased
Death
Neoplasm malignant (cancer tumour)
Rash
Vomiting
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood pressure increased

male:

n/a

What are the common drug interactions of Clarithromycin and Estraderm, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anaemia (lack of blood)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Headache (pain in head)
Interstitial lung disease
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Oedema (fluid collection in tissue)
Pericardial effusion (fluid around the heart)
Platelet count decreased
Pleural effusion (water on the lungs)
Pulmonary haemorrhage (acute bleeding from the lung)

30-39:

Blood pressure increased
Cerebral oedema (swelling of brain)
Communication disorder (speech and language disorder)
Cytomegalovirus infection
Encephalopathy (functioning of the brain is affected by some agent or condition)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

40-49:

n/a

50-59:

Sepsis (a severe blood infection that can lead to organ failure and death)
Rash
Vomiting

60+:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Rigors (an episode of shaking or exaggerated shivering)
Chest discomfort
Chest pain
Cough
Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)
Heart rate increased
Iron deficiency anaemia

What are the existing conditions these people have? *

Pseudomembranous Colitis (antibiotic-associated diarrhoea (aad), is an infection of the colon): 4 people, 33.33%
Gastric Ulcer (stomach ulcer): 4 people, 33.33%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 4 people, 33.33%
Headache (pain in head): 2 people, 16.67%
Renal Cell Carcinoma (a kidney cancer): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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