Zanaflex and Convulsions - a phase IV clinical study of FDA data

Summary:

Convulsions is reported as a side effect among people who take Zanaflex (tizanidine hydrochloride), especially for people who are female, 40-49 old, have been taking the drug for 1 - 6 months also take Avonex, and have Back pain.

The phase IV clinical study analyzes which people have Convulsions when taking Zanaflex. It is created by eHealthMe based on reports of 16,325 people who have side effects when taking Zanaflex from the FDA, and is updated regularly.

What is Zanaflex?

Zanaflex has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 17,476 Zanaflex users. Check the latest studies of Zanaflex.

What is Convulsions?

Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly) is found to be associated with 628 drugs and 199 conditions by eHealthMe. Check the latest studies of Convulsions.

On Jul, 21, 2026

16,325 people reported to have side effects when taking Zanaflex.
Among them, 39 people (0.24%) have Convulsions.

Among these 39 people:

How long have people been on Zanaflex when they have Convulsions? *

What is the gender of people who have Convulsions when taking Zanaflex? *

female: 57.89 %
male: 42.11 %

What is the age of people who have Convulsions when taking Zanaflex? *

What are other drugs people take besides Zanaflex? *

What are other side effects people have besides Convulsions? *

Fatigue (feeling of tiredness): 3 people, 7.69%
Confusion: 3 people, 7.69%
Pain In Limb: 3 people, 7.69%
Haemorrhagic Stroke (stroke caused by the rupture of a blood vessel in the brain): 3 people, 7.69%
White Blood Cell Count Decreased: 2 people, 5.13%
Oedema Peripheral (superficial swelling): 2 people, 5.13%
Cerebral Artery Thrombosis (clot formation in brain blood vessels): 2 people, 5.13%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 5.13%
Influenza Like Illness: 2 people, 5.13%
Fever: 2 people, 5.13%

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 2.56%
Back Pain: 1 person, 2.56%

* Approximation only. Some reports may have incomplete information.

Do you take Zanaflex and have Convulsions?

- Check whether Convulsions is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zanaflex:

Zanaflex (17,476 reports)

Convulsions treatments and more:

Convulsions (80 reports)

Browse all side effects of Zanaflex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Convulsions:

Convulsions (629 drugs)

Browse all the conditions that are associated with Convulsions:

Convulsions (199 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tizanidine hydrochloride (the active ingredients of Zanaflex) and Zanaflex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.