Claritin and Firazyr drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Claritin (loratadine) and Firazyr (icatibant acetate). Common drug interactions include hereditary angioedema among females and abdominal pain among males.
The phase IV clinical study analyzes what interactions people have when they take Claritin and Firazyr. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.
What is Claritin?
Claritin has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 77,315 Claritin users. Check the latest studies of Claritin.
What is Firazyr?
Firazyr has active ingredients of icatibant acetate. eHealthMe is studying from 5,650 Firazyr users. Check the latest studies of Firazyr.
47 people who take Claritin and Firazyr together, and have interactions are studied.

What are the common drug interactions of Claritin and Firazyr, by gender? *:
female:
- Hereditary angioedema (recurrent episodes of severe swelling)
- Pain in extremity
- Hospitalisation
- Sinusitis (inflammation of sinus)
- Headache (pain in head)
- Cardiac disorder
- Dyspnoea (difficult or laboured respiration)
- Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach)
- Blood copper increased
- Chest pain
male:
- Abdominal pain
- Angioedema (rapid swelling of the dermis)
- Injury
- Lethargy (tiredness)
- Nausea (feeling of having an urge to vomit)
- Otitis media (inflammation of the middle ear)
- Respiratory tract infection
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Urinary tract infection
- Vomiting
What are the common drug interactions of Claritin and Firazyr, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Drug ineffective
- Vomiting
30-39:
- Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach)
- Blood copper increased
- Cardiac disorder
- Chest pain
- Concussion (short loss of normal brain function in response to a head injury)
- Device occlusion
- Drug ineffective
- Dyspnoea (difficult or laboured respiration)
- Haematochezia (passage of stools containing blood)
- Head injury
40-49:
- Cardiomyopathy (weakening of the heart muscle)
- Hereditary angioedema (recurrent episodes of severe swelling)
- Death
- Protein c decreased
- Thrombosis (formation of a blood clot inside a blood vessel)
- Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
- Hospitalisation
- Hypersensitivity
- Sinusitis (inflammation of sinus)
50-59:
- Hereditary angioedema (recurrent episodes of severe swelling)
- Urticaria (rash of round, red welts on the skin that itch intensely)
- Muscle strain (an injury to a muscle in which the muscle fibres tear)
- Pain in extremity
- Emergency care
- Injection site urticaria (rash of round, red welts on the skin at injection site)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Back pain
- Pyrexia (fever)
- Bacterial infection
60+:
- Hereditary angioedema (recurrent episodes of severe swelling)
- Dizziness
- Oxygen saturation decreased
- Vaginal infection
- Infusion site swelling
- Colitis (inflammation of colon)
- Headache (pain in head)
- Influenza
- Urticaria (rash of round, red welts on the skin that itch intensely)
- Appendix disorder
What are the existing conditions these people have? *
- Hereditary Angioedema (recurrent episodes of severe swelling): 28 people, 59.57%
- Immune System Disorder: 17 people, 36.17%
- Stress And Anxiety: 4 people, 8.51%
- Pain: 3 people, 6.38%
- Nasopharyngitis (inflammation of the nasopharynx): 3 people, 6.38%
- Muscle Spasms (muscle contraction): 3 people, 6.38%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.38%
- Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 3 people, 6.38%
* Approximation only. Some reports may have incomplete information.
Do you take Claritin and Firazyr?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Claritin and Firazyr:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Claritin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Firazyr:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Claritin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Firazyr and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on loratadine and icatibant acetate (the active ingredients of Claritin and Firazyr, respectively), and Claritin and Firazyr (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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