Clonazepam and Alimta drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Clonazepam (clonazepam) and Alimta (pemetrexed disodium). Common drug interactions include pneumonia among females and thrombocytopenia among males.
The phase IV clinical study analyzes what interactions people have when they take Clonazepam and Alimta. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.
What is Clonazepam?
Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 146,270 Clonazepam users. Check the latest studies of Clonazepam.
What is Alimta?
Alimta has active ingredients of pemetrexed disodium. eHealthMe is studying from 7,702 Alimta users. Check the latest studies of Alimta.
23 people who take Clonazepam and Alimta together, and have interactions are studied.

What are the common drug interactions of Clonazepam and Alimta, by gender? *:
female:
- Pneumonia
- Pyrexia (fever)
- Neutropenia (an abnormally low number of neutrophils)
- Chest pain
- Dyspnoea (difficult or laboured respiration)
- Lobar pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung)
male:
- Thrombocytopenia (decrease of platelets in blood)
- Segmented hyalinising vasculitis (a chronic relapsing inflammatory condition of the blood vessels of the lower legs associated with nodular or purpuric skin lesions)
- Pleural effusion (water on the lungs)
- Pyrexia (fever)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Septic shock (shock due to blood infection)
- Coagulation time prolonged
- Cytolytic hepatitis (dissolution or destruction of a liver cell)
- Disease progression
- Fall
What are the common drug interactions of Clonazepam and Alimta, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Cardiotoxicity (damage to the heart muscle)
- Congestive cardiomyopathy (weakening of heart muscle)
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Ejection fraction decreased (systolic heart failure)
- Fatigue (feeling of tiredness)
- Pleural effusion (water on the lungs)
- Pneumonia
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Neutropenia (an abnormally low number of neutrophils)
- Angioedema (rapid swelling of the dermis)
60+:
- Thrombocytopenia (decrease of platelets in blood)
- Segmented hyalinising vasculitis (a chronic relapsing inflammatory condition of the blood vessels of the lower legs associated with nodular or purpuric skin lesions)
- Transaminases increased
- Septic shock (shock due to blood infection)
- Cytolytic hepatitis (dissolution or destruction of a liver cell)
- Neutropenia (an abnormally low number of neutrophils)
- Leukocytoclastic vasculitis (inflammation of small blood vessels (usually post-capillary venules in the dermis), characterized by palpable purpura)
What are the existing conditions these people have? *
- Lung Cancer Metastatic (lung cancer spreads to other parts): 8 people, 34.78%
- Lung Cancer - Non-Small Cell (lung cancer): 3 people, 13.04%
- Pulmonary Embolism (blockage of the main artery of the lung): 2 people, 8.70%
- Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 2 people, 8.70%
- Cancer Pain: 2 people, 8.70%
* Approximation only. Some reports may have incomplete information.
Do you take Clonazepam and Alimta?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Clonazepam (146,270 reports)
- Alimta (7,702 reports)
Browse all drug interactions of Clonazepam and Alimta:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Clonazepam:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Alimta:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clonazepam and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Alimta and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on clonazepam and pemetrexed disodium (the active ingredients of Clonazepam and Alimta, respectively), and Clonazepam and Alimta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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