Clonazepam and Dramamine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clonazepam (clonazepam) and Dramamine (dimenhydrinate). Common drug interactions include dry eye among females and depression among males.

The phase IV clinical study analyzes what interactions people have when they take Clonazepam and Dramamine. It is created by eHealthMe based on reports of 71 people who take the same drugs from the FDA, and is updated regularly.

What is Clonazepam?

Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 146,270 Clonazepam users. Check the latest studies of Clonazepam.

What is Dramamine?

Dramamine has active ingredients of dimenhydrinate. It is often used in motion sickness. eHealthMe is studying from 1,386 Dramamine users. Check the latest studies of Dramamine.



On Apr, 24, 2026

71 people who take Clonazepam and Dramamine together, and have interactions are studied.

Clonazepam and Dramamine drug interactions.

What are the common drug interactions of Clonazepam and Dramamine, by gender? *:

female:

  1. Dry eye (lack of adequate tears)
  2. Encephalitis (inflammation of the brain)
  3. Facial pain
  4. Head injury
  5. Hospitalisation
  6. Influenza like illness
  7. Laceration (tearing of soft body tissue)
  8. Large intestinal obstruction
  9. Memory impairment
  10. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)

male:

  1. Depression
  2. Bipolar disorder (mood disorder)
  3. Loss of consciousness
  4. Muscle spasms (muscle contraction)
  5. Myalgia (muscle pain)
  6. Sensory disturbance (sense disturbance)
  7. Somnolence (a state of near-sleep, a strong desire for sleep)
  8. Syncope (loss of consciousness with an inability to maintain postural tone)
  9. Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
  10. Burning sensation

What are the common drug interactions of Clonazepam and Dramamine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Akathisia (a movement disorder characterized by a feeling of inner restlessness)
  2. Energy increased
  3. Fatigue (feeling of tiredness)
  4. Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin)
  5. Hyperhidrosis (abnormally increased sweating)
  6. Nausea (feeling of having an urge to vomit)
  7. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  8. Restlessness (not able to rest)
  9. Ovarian cyst (fluid filled sac of the ovary)

40-49:

  1. Spinal fusion surgery
  2. Encephalitis (inflammation of the brain)
  3. Crying
  4. Dysgeusia (disorder of the sense of taste)
  5. Fatigue (feeling of tiredness)
  6. Feeling of despair
  7. Hepatic steatosis (fatty liver disease)
  8. Nephrolithiasis (calculi in the kidneys)
  9. Pulmonary congestion (congestion in the lungs)
  10. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)

50-59:

  1. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  2. Muscular weakness (muscle weakness)
  3. Nausea (feeling of having an urge to vomit)
  4. Oesophagitis (inflammation of oesophagus)
  5. Oral herpes (viral infection of mouth)
  6. Pyrexia (fever)
  7. Visual impairment
  8. Weight decreased
  9. Yawning (simultaneous inhalation of air and stretching of the eardrums, followed by exhalation of breath)
  10. Depression

60+:

  1. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  2. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  3. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  4. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  5. Death
  6. Depression
  7. Nausea (feeling of having an urge to vomit)
  8. Abdominal hernia
  9. Anaphylactic reaction (serious allergic reaction)
  10. Attention deficit hyperactivity disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 25 people, 35.21%
  2. Pain: 18 people, 25.35%
  3. High Blood Pressure: 16 people, 22.54%
  4. High Blood Cholesterol: 15 people, 21.13%
  5. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 12 people, 16.90%
  6. Depression: 12 people, 16.90%
  7. Nausea (feeling of having an urge to vomit): 11 people, 15.49%
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints): 9 people, 12.68%
  9. Indigestion: 9 people, 12.68%
  10. Blood Potassium Abnormal: 7 people, 9.86%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Clonazepam and Dramamine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Clonazepam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Dramamine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Clonazepam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dramamine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on clonazepam and dimenhydrinate (the active ingredients of Clonazepam and Dramamine, respectively), and Clonazepam and Dramamine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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