Clopra and Estraderm drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clopra (metoclopramide hydrochloride) and Estraderm (estradiol). Common drug interactions include hemiparesis among females and anaemia postoperative among males.

The phase IV clinical study analyzes what interactions people have when they take Clopra and Estraderm. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Clopra?

Clopra has active ingredients of metoclopramide hydrochloride. eHealthMe is studying from 81,430 Clopra users. Check the latest studies of Clopra.

What is Estraderm?

Estraderm has active ingredients of estradiol. It is often used in hormone replacement therapy. eHealthMe is studying from 3,441 Estraderm users. Check the latest studies of Estraderm.

On Jul, 11, 2026

28 people who take Clopra and Estraderm together, and have interactions are studied.

What are the common drug interactions of Clopra and Estraderm, by gender? *:

female:

Hemiparesis (weakness on one side of the body)
Hypoaesthesia (reduced sense of touch or sensation)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Dysarthria (speech disorder)
Fall
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Sepsis (a severe blood infection that can lead to organ failure and death)
Asthenia (weakness)

male:

Anaemia postoperative
Balance disorder
Platelet count decreased
Fall
Femur fracture
Fracture displacement
Limb asymmetry (consistent task discrepancy between the two lower limbs)
Limb deformity (functional disability of leg)
Lower limb fracture
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

What are the common drug interactions of Clopra and Estraderm, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal pain
Aggression
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Constipation
Crying
Depressed mood
Diarrhoea
Disturbance in attention
Hallucinations, mixed (sensations that appear real but are created by your mind -mixed)
Headache (pain in head)

40-49:

n/a

50-59:

Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Gait disturbance
Gastrointestinal inflammation (inflammation of stomach and intestine)
Headache (pain in head)
Hemianopia homonymous (visual field defect involving either the two right or the two left halves of the visual fields of both eyes)
Hyperlipidaemia (presence of excess lipids in the blood)
Lethargy (tiredness)
Malaise (a feeling of general discomfort or uneasiness)
Mitral valve incompetence (inefficient heart valve)
Mitral valve prolapse (heart's mitral valve doesn't work well)

60+:

Acute myocardial infarction (acute heart attack)
Abdominal distension
Rib fracture
Vaginal discharge
Abdominal discomfort
Abdominal pain upper
Accidental poisoning
Activities of daily living impaired
Altered state of consciousness (altered state of mind)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)

What are the existing conditions these people have? *

High Blood Pressure: 5 people, 17.86%
High Blood Cholesterol: 5 people, 17.86%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 14.29%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 14.29%
Menopause (end of monthly cycles in women): 4 people, 14.29%
Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 4 people, 14.29%
Reflux Oesophagitis (an oesophageal mucosal injury that occurs of gastric contents into the oesophagus): 3 people, 10.71%
Osteoporosis (bones weak and more likely to break): 3 people, 10.71%
Nausea And Vomiting: 3 people, 10.71%
Nausea (feeling of having an urge to vomit): 3 people, 10.71%

* Approximation only. Some reports may have incomplete information.

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