Clozaril and Cephalexin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Clozaril (clozapine) and Cephalexin (cephalexin). Common drug interactions include pain among females and influenza like illness among males.
The phase IV clinical study analyzes what interactions people have when they take Clozaril and Cephalexin. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.
What is Clozaril?
Clozaril has active ingredients of clozapine. It is often used in schizophrenia. eHealthMe is studying from 65,127 Clozaril users. Check the latest studies of Clozaril.
What is Cephalexin?
Cephalexin has active ingredients of cephalexin. It is often used in infection. eHealthMe is studying from 30,580 Cephalexin users. Check the latest studies of Cephalexin.
44 people who take Clozaril and Cephalexin together, and have interactions are studied.

What are the common drug interactions of Clozaril and Cephalexin, by gender? *:
female:
- Pain
- Relapsing fever (bacterial infection characterized by recurring episodes of fever, headache, muscle and joint aches, and nausea)
- Sinusitis (inflammation of sinus)
- Subcutaneous abscess
- Toxoplasmosis (a parasitic disease caused by the protozoan toxoplasma gondii)
- Vomiting
- Vulvovaginal candidiasis (vulvovaginal infection by fungi)
- Weight increased
- Wheezing (a high-pitched whistling sound made while you breath)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
male:
- Influenza like illness
- Renal failure acute (rapid kidney dysfunction)
- White blood cell count decreased
- Blood creatine phosphokinase increased
- Blood creatinine increased
- Chondromatosis (benign tumour of the soft tissues, usually occurring around the joints)
- Depression
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Hallucination, auditory (perceiving sounds without auditory stimulus)
- Orchitis noninfective (non infectious inflammation of the testes)
What are the common drug interactions of Clozaril and Cephalexin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Influenza like illness
- Renal failure acute (rapid kidney dysfunction)
- Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
- Petechiae (a small red or purple spot caused by bleeding into the skin)
- Lower respiratory tract infection
- Urine output decreased
- Blood creatine phosphokinase increased
- Blood creatinine increased
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Malaise (a feeling of general discomfort or uneasiness)
40-49:
- Diarrhoea
- Nausea (feeling of having an urge to vomit)
- Obesity (having too much body fat)
- Weight increased
- Abdominal discomfort
- Abdominal pain upper
- Anaemia (lack of blood)
- Arthralgia (joint pain)
- Basedow's disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones)
- Blood cholesterol increased
50-59:
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Breast cancer
- Breast cancer female
- Platelet count decreased
- Aggression
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Constipation
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
- Diarrhoea
60+:
- Cardiac failure congestive
- Coarctation of the aorta (narrowing of the part of aorta)
- Bone disorder
- Bone erosion
- Bone fragmentation
- Bone loss
- Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)
- Cardiac disorder
- Compression fracture (fracture due to pressure caused by injury)
- Constipation
What are the existing conditions these people have? *
- Stress And Anxiety: 10 people, 22.73%
- Depression: 10 people, 22.73%
- Sleep Disorder: 8 people, 18.18%
- Bipolar Disorder (mood disorder): 7 people, 15.91%
- Anger: 5 people, 11.36%
- Pain: 3 people, 6.82%
* Approximation only. Some reports may have incomplete information.
Do you take Clozaril and Cephalexin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Clozaril (65,127 reports)
- Cephalexin (30,580 reports)
Browse all drug interactions of Clozaril and Cephalexin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Clozaril:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cephalexin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clozaril and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cephalexin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Grover S, Sahoo S, "Clozapine induced akathisia: A case report and review of the evidence", Indian journal of pharmacology, 2015 Jan .
- Agrawal A, Rao M, Jasdanwala S, Mathur A, Eng M, "Cephalexin Induced Cholestatic Jaundice", Case reports in gastrointestinal medicine, 2014 Aug .
- Yaylaci S, Yilmaz EU, Guclu E, Kumsar NA, Tamer A, Karabay O, "Clozapine-Induced Febrile Neutropenia and Cellulitis", Turkish journal of emergency medicine, 2014 Mar .
- Grover S, Sahoo S, "Clozapine induced akathisia: A case report and review of the evidence", Indian journal of pharmacology, 2015 Jan .
- Agrawal A, Rao M, Jasdanwala S, Mathur A, Eng M, "Cephalexin Induced Cholestatic Jaundice", Case reports in gastrointestinal medicine, 2014 Aug .
- Yaylaci S, Yilmaz EU, Guclu E, Kumsar NA, Tamer A, Karabay O, "Clozapine-Induced Febrile Neutropenia and Cellulitis", Turkish journal of emergency medicine, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on clozapine and cephalexin (the active ingredients of Clozaril and Cephalexin, respectively), and Clozaril and Cephalexin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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