Codeine sulfate and Paxil drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Codeine sulfate (codeine sulfate) and Paxil (paroxetine hydrochloride). Common drug interactions include tooth deposit among females and renal failure among males.
The phase IV clinical study analyzes what interactions people have when they take Codeine sulfate and Paxil. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.
What is Codeine sulfate?
Codeine sulfate has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 4,510 Codeine sulfate users. Check the latest studies of Codeine sulfate.
What is Paxil?
Paxil has active ingredients of paroxetine hydrochloride. It is often used in depression. eHealthMe is studying from 92,546 Paxil users. Check the latest studies of Paxil.
32 people who take Codeine sulfate and Paxil together, and have interactions are studied.

What are the common drug interactions of Codeine Sulfate and Paxil, by gender? *:
female:
- Tooth deposit
- Anaemia (lack of blood)
- Atelectasis (partial or complete collapse of the lung)
- Back pain
- Bone disorder
- Nausea (feeling of having an urge to vomit)
- Pain in extremity
- Pleural effusion (water on the lungs)
- Rash
- Actinomycosis (infection that causes sores, or abscesses)
male:
- Renal failure (kidney dysfunction)
- Abscess limb (limb infection)
- Back injury
- Back pain
- Balance disorder
- Benign prostatic hyperplasia (benign enlargement of the prostate)
- Bladder cancer
- Bladder mass
- Bladder neoplasm (bladder tumour)
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
What are the common drug interactions of Codeine Sulfate and Paxil, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Abdominal discomfort
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Drug ineffective
- Gastric disorder (disease of stomach)
- Injury
- Pulmonary embolism (blockage of the main artery of the lung)
- Vomiting
- Weight decreased
30-39:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
40-49:
- Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
- Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
- Dental caries
- Diaphragmatic paralysis (acquired dysfunction of the phrenic nerve)
- Diarrhoea
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Febrile neutropenia (fever with reduced white blood cells)
- Gingival erythema (redness of gums)
- Haematochezia (passage of stools containing blood)
- Insomnia (sleeplessness)
50-59:
n/a
60+:
- Actinomycosis (infection that causes sores, or abscesses)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Face oedema (swelling of face)
- Gingival swelling (gums swelling)
- Hyperplasia (enlargement of an organ or tissue)
- Hypoaesthesia (reduced sense of touch or sensation)
- Impaired healing
- Inflammation
- Myofascial pain syndrome (a painful condition that affects the muscles and the sheath of the tissue)
- Oral discomfort (pain or irritation in mouth)
What are the existing conditions these people have? *
- Breast Cancer: 13 people, 40.62%
- Metastases To Bone (cancer spreads to bone): 12 people, 37.50%
- Stress And Anxiety: 9 people, 28.12%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 25.00%
- Bone Pain: 6 people, 18.75%
- Intracranial Aneurysm (bulging, weak area in the wall of a cranial artery): 3 people, 9.38%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 6.25%
- Nerve Injury: 2 people, 6.25%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 6.25%
- High Blood Pressure: 2 people, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Codeine sulfate and Paxil?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Codeine sulfate (4,510 reports)
- Paxil (92,546 reports)
Browse all drug interactions of Codeine sulfate and Paxil:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Codeine sulfate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Paxil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Codeine sulfate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Paxil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
- Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
How the study uses the data?
The study uses data from the FDA. It is based on codeine sulfate and paroxetine hydrochloride (the active ingredients of Codeine sulfate and Paxil, respectively), and Codeine sulfate and Paxil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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