Cogentin and Vitamin c drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cogentin (benztropine mesylate) and Vitamin c (l-ascorbic acid). Common drug interactions include cellulitis among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Cogentin and Vitamin c. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Cogentin?

Cogentin has active ingredients of benztropine mesylate. It is often used in tardive dyskinesia. eHealthMe is studying from 7,692 Cogentin users. Check the latest studies of Cogentin.

What is Vitamin c?

Vitamin c has active ingredients of l-ascorbic acid. It is often used in immune response. eHealthMe is studying from 92,472 Vitamin c users. Check the latest studies of Vitamin c.



On Aug, 03, 2026

46 people who take Cogentin and Vitamin c together, and have interactions are studied.

Cogentin and Vitamin c drug interactions.

What are the common drug interactions of Cogentin and Vitamin C, by gender? *:

female:

  1. Cellulitis (infection under the skin)
  2. Cerumen impaction
  3. Chest pain
  4. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  5. Coccidioidomycosis (serious disease of the lungs and other tissues, caused by the fungus coccidioides immitis)
  6. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  7. Contusion (a type of hematoma of tissue in which capillaries)
  8. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  9. Decreased interest
  10. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

male:

  1. Arthralgia (joint pain)
  2. Chest pain
  3. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  4. Chest discomfort
  5. Chills (felling of cold)
  6. Cold sweat
  7. Confusional state
  8. Delusion (a false belief or opinion)
  9. Diarrhoea
  10. Dysgeusia (disorder of the sense of taste)

What are the common drug interactions of Cogentin and Vitamin C, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Arrhythmia (irregular heartbeat)
  2. Depression
  3. Adverse drug reaction
  4. Anxiety
  5. Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem)
  6. Bladder disorder
  7. Blepharospasm (any abnormal contraction or twitch of the eyelid)
  8. Disturbance in attention
  9. Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
  10. Eye disorder

40-49:

  1. Arthralgia (joint pain)
  2. Chest pain
  3. Dizziness
  4. Headache (pain in head)
  5. Pain in extremity
  6. Abdominal pain
  7. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  8. Asthenia (weakness)
  9. Back pain
  10. Balance disorder

50-59:

  1. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  2. Myalgia (muscle pain)
  3. Neuropathy peripheral (surface nerve damage)
  4. Nodule (a growth of abnormal tissue)
  5. Oedema (fluid collection in tissue)
  6. Olfactory nerve disorder (disorders of taste and smell)
  7. Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
  8. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  9. Osteonecrosis of jaw (death of bone of jaw)
  10. Osteoporosis (bones weak and more likely to break)

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Contusion (a type of hematoma of tissue in which capillaries)
  3. Dizziness
  4. Fatigue (feeling of tiredness)
  5. Headache (pain in head)
  6. Hypertensive heart disease
  7. Hypoaesthesia (reduced sense of touch or sensation)
  8. Intraocular pressure increased
  9. Neuralgia (pain in one or more nerves)
  10. Oral infection

What are the existing conditions these people have? *

  1. Bipolar Disorder (mood disorder): 6 people, 13.04%
  2. Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 5 people, 10.87%
  3. Depression: 5 people, 10.87%
  4. Stress And Anxiety: 4 people, 8.70%
  5. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 6.52%
  6. Psychotic Disorder: 3 people, 6.52%
  7. Multiple Myeloma (cancer of the plasma cells): 3 people, 6.52%
  8. Insomnia (sleeplessness): 3 people, 6.52%
  9. Constipation: 3 people, 6.52%
  10. Affective Disorder (mental disorder): 3 people, 6.52%

* Approximation only. Some reports may have incomplete information.

Do you take Cogentin and Vitamin c?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cogentin and Vitamin c:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cogentin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Vitamin c:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cogentin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vitamin c and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on benztropine mesylate and l-ascorbic acid (the active ingredients of Cogentin and Vitamin c, respectively), and Cogentin and Vitamin c (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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