Combivir and Lopressor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Combivir (lamivudine; zidovudine) and Lopressor (metoprolol tartrate). Common drug interactions include pernicious anaemia among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Combivir and Lopressor. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Combivir?

Combivir has active ingredients of lamivudine; zidovudine. It is often used in hiv infection. eHealthMe is studying from 15,450 Combivir users. Check the latest studies of Combivir.

What is Lopressor?

Lopressor has active ingredients of metoprolol tartrate. It is often used in high blood pressure. eHealthMe is studying from 33,152 Lopressor users. Check the latest studies of Lopressor.



On Jul, 13, 2026

25 people who take Combivir and Lopressor together, and have interactions are studied.

Combivir and Lopressor drug interactions.

What are the common drug interactions of Combivir and Lopressor, by gender? *:

female:

  1. Pernicious anaemia (anaemia due to lack of vitamin b12)
  2. Premature labour
  3. Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
  4. Thrombosis (formation of a blood clot inside a blood vessel)
  5. Tooth disorder (tooth disease)
  6. Uterine disorder
  7. Abdominal pain
  8. Blood pressure fluctuation
  9. Headache (pain in head)
  10. Intra-uterine death

male:

  1. Anxiety
  2. Emotional distress
  3. Drug resistance (reduction in effectiveness of a drug)
  4. Gait disturbance
  5. Osteoporosis (bones weak and more likely to break)
  6. Renal impairment (severely reduced kidney function)
  7. Blood creatinine increased
  8. Fatigue (feeling of tiredness)
  9. Mobility decreased (ability to move is reduced)
  10. Proteinuria (presence of protein in the urine)

What are the common drug interactions of Combivir and Lopressor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Decreased activity
  4. Depression
  5. Dyspnoea (difficult or laboured respiration)
  6. Emotional distress
  7. Fatigue (feeling of tiredness)
  8. Hallucination (an experience involving the perception of something not present)
  9. Impaired work ability
  10. Osteoporosis (bones weak and more likely to break)

30-39:

  1. Intra-uterine death
  2. Oedema peripheral (superficial swelling)
  3. Pre-eclampsia (high blood pressure and significant amounts of protein in the urine of a pregnant woman)
  4. Proteinuria (presence of protein in the urine)
  5. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  6. Anxiety
  7. Chronic kidney disease
  8. Emotional distress
  9. Pain
  10. Abdominal pain

40-49:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Emotional distress
  4. Pain
  5. Chronic kidney disease
  6. Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
  7. Bone pain
  8. Drug resistance (reduction in effectiveness of a drug)
  9. Gait disturbance
  10. Renal impairment (severely reduced kidney function)

50-59:

  1. Chronic kidney disease
  2. Osteoporosis (bones weak and more likely to break)
  3. Emotional distress
  4. Pain
  5. Renal failure (kidney dysfunction)
  6. Angina pectoris (chest pain due to ischemia of the heart muscle)
  7. Blood creatinine increased
  8. Cardiac failure congestive
  9. Depression
  10. Intervertebral disc degeneration (spinal disc degeneration)

60+:

  1. Chronic kidney disease
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Anxiety
  4. Emotional distress
  5. Mobility decreased (ability to move is reduced)
  6. Pain
  7. Proteinuria (presence of protein in the urine)
  8. Neoplasm malignant (cancer tumour)

What are the existing conditions these people have? *

  1. Hiv Infection: 18 people, 72.00%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 12.00%
  3. Depression: 3 people, 12.00%
  4. Cardiac Disorder: 3 people, 12.00%
  5. Tremor (trembling or shaking movements in one or more parts of your body): 2 people, 8.00%
  6. Stress And Anxiety: 2 people, 8.00%
  7. Stable Angina (a constant chest pain): 2 people, 8.00%
  8. Post-Traumatic Stress Disorder: 2 people, 8.00%
  9. Pain: 2 people, 8.00%
  10. Muscle Spasms (muscle contraction): 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

Do you take Combivir and Lopressor?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Combivir and Lopressor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Combivir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lopressor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Combivir and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lopressor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on lamivudine; zidovudine and metoprolol tartrate (the active ingredients of Combivir and Lopressor, respectively), and Combivir and Lopressor (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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