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Zantac 150 and Urticaria - a phase IV clinical study of FDA data

Summary:

Urticaria is reported as a side effect among people who take Zantac 150 (ranitidine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Synthroid, and have Hypothyroidism.

The phase IV clinical study analyzes which people have Urticaria when taking Zantac 150. It is created by eHealthMe based on reports of 5,708 people who have side effects when taking Zantac 150 from the FDA, and is updated regularly.

What is Zantac 150?

Zantac 150 has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 6,519 Zantac 150 users. Check the latest studies of Zantac 150.

What is Urticaria?

Urticaria (rash of round, red welts on the skin that itch intensely) is found to be associated with 2,622 drugs and 2,952 conditions by eHealthMe. Check the latest studies of Urticaria.

On Jul, 13, 2026

5,708 people reported to have side effects when taking Zantac 150.
Among them, 57 people (1.0%) have Urticaria.

Could Zantac 150 cause Urticaria?

Among these 57 people:

How long have people been on Zantac 150 when they have Urticaria? *

  • < 1 month: 89.47 %
  • 1 - 6 months: 10.53 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Urticaria when taking Zantac 150? *

  • female: 70.91 %
  • male: 29.09 %

What is the age of people who have Urticaria when taking Zantac 150? *

  • 0-1: 0.0 %
  • 2-9: 2.5 %
  • 10-19: 5.0 %
  • 20-29: 7.5 %
  • 30-39: 7.5 %
  • 40-49: 12.5 %
  • 50-59: 17.5 %
  • 60+: 47.5 %

What are other drugs people take besides Zantac 150? *

  1. Lisinopril: 4 people, 7.02%
  2. Synthroid: 4 people, 7.02%
  3. Aspirin: 3 people, 5.26%
  4. Lipitor: 3 people, 5.26%
  5. Klor-Con: 2 people, 3.51%
  6. Miralax: 2 people, 3.51%
  7. Meclizine: 2 people, 3.51%
  8. Levothyroxine Sodium: 2 people, 3.51%
  9. Lasix: 2 people, 3.51%
  10. Furosemide: 2 people, 3.51%

What are other side effects people have besides Urticaria? *

  1. Itching: 15 people, 26.32%
  2. Rashes (redness): 11 people, 19.30%
  3. Hypersensitivity: 7 people, 12.28%
  4. Oedema Peripheral (superficial swelling): 5 people, 8.77%
  5. Lip Swelling: 5 people, 8.77%
  6. Pruritus Generalised (generalized itching): 4 people, 7.02%
  7. Nausea (feeling of having an urge to vomit): 4 people, 7.02%
  8. Joint Swelling: 4 people, 7.02%
  9. Abdominal Pain Upper: 4 people, 7.02%
  10. Throat Tightness: 3 people, 5.26%

What are the existing conditions these people have? *

  1. Hyperchlorhydria (gastric acid levels are higher in stomach): 3 people, 5.26%
  2. Stress And Anxiety: 3 people, 5.26%
  3. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 5.26%
  4. Urinary Tract Infection: 2 people, 3.51%
  5. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 3.51%
  6. Bone Density Decreased: 2 people, 3.51%
  7. Dizziness: 2 people, 3.51%
  8. Fluid Retention (an abnormal accumulation of fluid in the blood): 2 people, 3.51%
  9. Heart Rate Increased: 2 people, 3.51%
  10. High Blood Cholesterol: 2 people, 3.51%

* Approximation only. Some reports may have incomplete information.

Do you take Zantac 150 and have Urticaria?

- Check whether Urticaria is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zantac 150:

Urticaria treatments and more:

How severe was Urticaria and when was it recovered:

Expand to all the drugs that have ingredients of ranitidine hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Zantac 150:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Urticaria:

Browse all the conditions that are associated with Urticaria:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on ranitidine hydrochloride (the active ingredients of Zantac 150) and Zantac 150 (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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