Lantus and Pyoderma gangrenosum - a phase IV clinical study of FDA data

Summary:

Pyoderma gangrenosum is reported as a side effect among people who take Lantus (insulin glargine recombinant), especially for people who are female, 40-49 old, also take Apidra Solostar, and have Crohn's disease.

The phase IV clinical study analyzes which people have Pyoderma gangrenosum when taking Lantus. It is created by eHealthMe based on reports of 190,478 people who have side effects when taking Lantus from the FDA, and is updated regularly.

What is Lantus?

Lantus has active ingredients of insulin glargine recombinant. It is often used in diabetes. eHealthMe is studying from 191,782 Lantus users. Check the latest studies of Lantus.

What is Pyoderma gangrenosum?

Pyoderma gangrenosum (ulcerating condition of skin that results in heaped borders with a typical appearance) is found to be associated with 306 drugs and 346 conditions by eHealthMe. Check the latest studies of Pyoderma gangrenosum.

On Jul, 13, 2026

190,478 people reported to have side effects when taking Lantus.
Among them, 25 people (0.01%) have Pyoderma gangrenosum.

Could Lantus cause Pyoderma gangrenosum?

Among these 25 people:

What is the gender of people who have Pyoderma gangrenosum when taking Lantus? *

female: 65.22 %
male: 34.78 %

What is the age of people who have Pyoderma gangrenosum when taking Lantus? *

What are other drugs people take besides Lantus? *

What are other side effects people have besides Pyoderma gangrenosum? *

Abdominal Abscess (collection of pus in abdomen): 9 people, 36.00%
Infusion Site Oedema (swelling from excessive accumulation of watery fluid from infusion site): 9 people, 36.00%
Abdominal Pain Upper: 9 people, 36.00%
Canker Sores (painful, open sore in the mouth): 9 people, 36.00%
Colostomy Infection (infection of colon opening out of body): 9 people, 36.00%
Weight Fluctuation: 9 people, 36.00%
Headache (pain in head): 9 people, 36.00%
Infusion Site Extravasation (flow of (blood or lymph) from infusion site): 9 people, 36.00%
Poor Venous Access: 9 people, 36.00%
Haematochezia (passage of stools containing blood): 7 people, 28.00%

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 13 people, 52.00%
High Blood Pressure: 4 people, 16.00%
Insomnia (sleeplessness): 3 people, 12.00%
Herpes Zoster: 3 people, 12.00%
Hepatocellular Carcinoma (liver cancer): 3 people, 12.00%
Hepatitis B: 3 people, 12.00%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 3 people, 12.00%
Cardiac Failure: 2 people, 8.00%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 4.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Lantus and have Pyoderma gangrenosum?

- Check whether Pyoderma gangrenosum is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Lantus:

Lantus (191,782 reports)

Browse all side effects of Lantus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pyoderma gangrenosum:

Pyoderma gangrenosum (306 drugs)

Browse all the conditions that are associated with Pyoderma gangrenosum:

Pyoderma gangrenosum (346 conditions)

Related publications that referenced our studies

Hania A, "Pyoderma Gangrenosum in a Patient With Systemic Lupus Erythematosus: Case Report", Journal of Medical Cases, 2014 Aug .
Hania A, "Pyoderma Gangrenosum in a Patient With Systemic Lupus Erythematosus: Case Report", Journal of Medical Cases, 2014 Aug .

How the study uses the data?

The study uses data from the FDA. It is based on insulin glargine recombinant (the active ingredients of Lantus) and Lantus (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.