Combivir and Ribavirin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Combivir (lamivudine; zidovudine) and Ribavirin (ribavirin). Common drug interactions include nausea among females and blood bilirubin increased among males.

The phase IV clinical study analyzes what interactions people have when they take Combivir and Ribavirin. It is created by eHealthMe based on reports of 67 people who take the same drugs from the FDA, and is updated regularly.

What is Combivir?

Combivir has active ingredients of lamivudine; zidovudine. It is often used in hiv infection. eHealthMe is studying from 15,450 Combivir users. Check the latest studies of Combivir.

What is Ribavirin?

Ribavirin has active ingredients of ribavirin. It is often used in hepatitis c. eHealthMe is studying from 78,532 Ribavirin users. Check the latest studies of Ribavirin.

On Jul, 12, 2026

67 people who take Combivir and Ribavirin together, and have interactions are studied.

Combivir and Ribavirin drug interactions.

What are the common drug interactions of Combivir and Ribavirin, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Polydipsia (excessive thirst)
Vision blurred
Abdominal pain
Abdominal pain upper
Blood potassium decreased
Cerebral disorder (brain disease)
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Decreased appetite
Diarrhoea

male:

Blood bilirubin increased
Lipodystrophy acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired)
Hepatosplenomegaly (enlargement of both the liver and the spleen)
Retinal detachment (a disorder of the eye in which the retina peels away from its underlying layer of support tissue)
Alanine aminotransferase increased
Depression
Dyspnoea (difficult or laboured respiration)
Abdominal pain upper
Anaemia (lack of blood)
Aspartate aminotransferase increased

What are the common drug interactions of Combivir and Ribavirin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain upper
Abnormal dreams
Alanine aminotransferase increased
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Aspartate aminotransferase increased
Atrioventricular block (heart block)
Atrioventricular block complete (heart block complete)
Atrioventricular block second degree (heart block second degree)
Balance disorder

30-39:

Fatigue (feeling of tiredness)
Thirst
Weight decreased
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Neuropathic pain (pain due to nerve inflammation and damage)
Abdominal pain upper
Diarrhoea
Glycosylated haemoglobin increased
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Hepatic failure (liver failure)

40-49:

Thrombocytopenia (decrease of platelets in blood)
Tinnitus (a ringing in the ears)
Transaminases increased
Ventricular extrasystoles (premature cardiac contraction)
Vomiting
Vulvar dysplasia (vulval dysplasia means that there are cells that are no longer normal and may be trying to become a cancer)
White blood cell count increased
Lipodystrophy acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired)
Hepatic steatosis (fatty liver disease)
Lipohypertrophy (a lump under the skin caused by accumulation of extra fat at the site of many subcutaneous injections of insulin)

50-59:

Malaise (a feeling of general discomfort or uneasiness)
Platelet count decreased
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood pressure increased
Cough
Depression
Drug screen positive
Dyspnoea (difficult or laboured respiration)
Overdose

60+:

Hyperglycaemia (high blood sugar)
Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
Dyspnoea exertional (breathlessness or shortness of breath)
Fatigue (feeling of tiredness)
Headache (pain in head)
Homicidal ideation (thoughts about human killing another human)
Pyrexia (fever)
Suicidal ideation

What are the existing conditions these people have? *

Hiv Infection: 28 people, 41.79%

* Approximation only. Some reports may have incomplete information.

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