Compazine and Aricept drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Compazine (prochlorperazine maleate) and Aricept (donepezil hydrochloride). Common drug interactions include immunodeficiency common variable among females and fall among males.

The phase IV clinical study analyzes what interactions people have when they take Compazine and Aricept. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Compazine?

Compazine has active ingredients of prochlorperazine maleate. It is often used in indigestion. eHealthMe is studying from 13,646 Compazine users. Check the latest studies of Compazine.

What is Aricept?

Aricept has active ingredients of donepezil hydrochloride. It is often used in alzheimer's disease. eHealthMe is studying from 24,756 Aricept users. Check the latest studies of Aricept.

On Jul, 16, 2026

44 people who take Compazine and Aricept together, and have interactions are studied.

Compazine and Aricept drug interactions.

What are the common drug interactions of Compazine and Aricept, by gender? *:

female:

Immunodeficiency common variable
Leukaemia (blood or bone marrow cancer)
Wheezing (a high-pitched whistling sound made while you breath)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Chronic kidney disease
Confusional state
Depression
Dysphagia (a condition in which swallowing is difficult or painful)
Fatigue (feeling of tiredness)
Glossodynia (a burning or painful sensation in the tongue)

male:

Fall
Fatigue (feeling of tiredness)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Abdominal pain
Balance disorder
Glaucoma (increased fluid pressure in the eye with vision loss)
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Hypertension (high blood pressure)
Metastases to the mediastinum (cancer spreads to mediastinum)
Pulmonary mass

What are the common drug interactions of Compazine and Aricept, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Immunodeficiency common variable
Leukaemia (blood or bone marrow cancer)
Wheezing (a high-pitched whistling sound made while you breath)
Agitation (state of anxiety or nervous excitement)
Cutaneous lupus erythematosus (own immune system attacks various cells causing a wide variety of signs and symptoms)
Emotional disorder
Glaucoma (increased fluid pressure in the eye with vision loss)
Homicidal ideation (thoughts about human killing another human)
Post-traumatic stress disorder
Asthma

60+:

Fatigue (feeling of tiredness)
Failure to thrive (inadequate weight gain and physical growth in children)
Hypertension (high blood pressure)
Abdominal pain
Decreased appetite
Pneumonia
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Metastases to the mediastinum (cancer spreads to mediastinum)
Pulmonary mass
Renal disorder (kidney disease)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 12 people, 27.27%
Asthma: 7 people, 15.91%
Nausea (feeling of having an urge to vomit): 6 people, 13.64%
Indigestion: 6 people, 13.64%
Depression: 4 people, 9.09%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 3 people, 6.82%
High Blood Pressure: 3 people, 6.82%
Dementia (madness): 3 people, 6.82%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 6.82%

* Approximation only. Some reports may have incomplete information.

Do you take Compazine and Aricept?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously