Comtan and M.v.i. drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Comtan (entacapone) and M.v.i. (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e). Common drug interactions include blood pressure increased among females and obsessive-compulsive disorder among males.
The phase IV clinical study analyzes what interactions people have when they take Comtan and M.v.i.. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Comtan?
Comtan has active ingredients of entacapone. It is often used in parkinson's disease. eHealthMe is studying from 3,979 Comtan users. Check the latest studies of Comtan.
What is M.v.i.?
M.v.i. has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. eHealthMe is studying from 2,498 M.v.i. users. Check the latest studies of M.v.i..
11 people who take Comtan and M.v.i. together, and have interactions are studied.

What are the common drug interactions of Comtan and M.V.I., by gender? *:
female:
- Blood pressure increased
- Feeling jittery
- Hot flush (sudden feelings of heat)
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Vision blurred
- Haemorrhage (bleeding)
- Incision site haemorrhage (bleeding from incision site)
male:
- Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
- Pathological gambling
- Decreased interest
- Dizziness
- Emotional distress
- Fear
- Pain
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Depression
- Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
What are the common drug interactions of Comtan and M.V.I., by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Blood pressure increased
- Feeling jittery
- Hot flush (sudden feelings of heat)
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Vision blurred
- Haemorrhage (bleeding)
- Incision site haemorrhage (bleeding from incision site)
What are the existing conditions these people have? *
- Pain: 7 people, 63.64%
- Depression: 5 people, 45.45%
- Stress And Anxiety: 4 people, 36.36%
- Nausea (feeling of having an urge to vomit): 4 people, 36.36%
- Insomnia (sleeplessness): 4 people, 36.36%
- Drowsiness: 4 people, 36.36%
- Back Pain: 4 people, 36.36%
- Abdominal Pain: 4 people, 36.36%
- Psychotic Disorder: 3 people, 27.27%
- Joint Pain: 2 people, 18.18%
* Approximation only. Some reports may have incomplete information.
Do you take Comtan and M.v.i.?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Comtan and M.v.i.:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Comtan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of M.v.i.:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Comtan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between M.v.i. and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on entacapone and ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (the active ingredients of Comtan and M.v.i., respectively), and Comtan and M.v.i. (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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