Copegus and Glucophage drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Copegus (ribavirin) and Glucophage (metformin hydrochloride). Common drug interactions include dehydration among females and white blood cell count decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Copegus and Glucophage. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.

What is Copegus?

Copegus has active ingredients of ribavirin. It is often used in hepatitis c. eHealthMe is studying from 15,115 Copegus users. Check the latest studies of Copegus.

What is Glucophage?

Glucophage has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 60,851 Glucophage users. Check the latest studies of Glucophage.

On Jul, 25, 2026

51 people who take Copegus and Glucophage together, and have interactions are studied.

Copegus and Glucophage drug interactions.

What are the common drug interactions of Copegus and Glucophage, by gender? *:

female:

Dehydration (dryness resulting from the removal of water)
Diarrhoea
Infection
Platelet count decreased
Sepsis (a severe blood infection that can lead to organ failure and death)
Vomiting
Burning sensation
Fatigue (feeling of tiredness)
Generalised oedema (swelling all over the body)
Pruritus (severe itching of the skin)

male:

White blood cell count decreased
Fatigue (feeling of tiredness)
Syncope (loss of consciousness with an inability to maintain postural tone)
Blood glucose increased
Blood testosterone decreased
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)
Cardiomyopathy (weakening of the heart muscle)

What are the common drug interactions of Copegus and Glucophage, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Nausea (feeling of having an urge to vomit)
Neutropenia (an abnormally low number of neutrophils)
Pancreatitis (inflammation of pancreas)
Post streptococcal glomerulonephritis (inflammation of the kidney tubules)
Anaemia (lack of blood)
Burning sensation
Dizziness
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Generalised oedema (swelling all over the body)

50-59:

White blood cell count decreased
Fatigue (feeling of tiredness)
Weight decreased
Arthralgia (joint pain)
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Viith nerve paralysis
Diarrhoea
Dysgeusia (disorder of the sense of taste)
Headache (pain in head)

60+:

Anaemia (lack of blood)
Renal failure (kidney dysfunction)
Bipolar disorder (mood disorder)
Diarrhoea
Haemorrhage (bleeding)
Infection
Lipase increased
Neutropenia (an abnormally low number of neutrophils)
Oesophageal candidiasis (fungal infection of oesophagus)
Oesophagitis (inflammation of oesophagus)

What are the existing conditions these people have? *

High Blood Pressure: 16 people, 31.37%
Type 2 Diabetes: 9 people, 17.65%
Anaemia (lack of blood): 4 people, 7.84%
Hiv Infection: 3 people, 5.88%
Hepatitis (inflammation of the liver): 3 people, 5.88%
Depression: 3 people, 5.88%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 3 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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