Coreg cr and Simvastatin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Coreg cr (carvedilol phosphate) and Simvastatin (simvastatin). Common drug interactions include heart rate increased among females and abnormal behaviour among males.

The phase IV clinical study analyzes what interactions people have when they take Coreg cr and Simvastatin. It is created by eHealthMe based on reports of 56 people who take the same drugs from the FDA, and is updated regularly.

What is Coreg cr?

Coreg cr has active ingredients of carvedilol phosphate. It is often used in high blood pressure. eHealthMe is studying from 1,628 Coreg cr users. Check the latest studies of Coreg cr.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,969 Simvastatin users. Check the latest studies of Simvastatin.

On Jul, 05, 2026

56 people who take Coreg cr and Simvastatin together, and have interactions are studied.

Coreg cr and Simvastatin drug interactions.

What are the common drug interactions of Coreg Cr and Simvastatin, by gender? *:

female:

Heart rate increased
Herpes zoster
Hypotension (abnormally low blood pressure)
Increased appetite
Lymphadenopathy (disease or enlargement of lymph nodes)
Memory impairment
Mobility decreased (ability to move is reduced)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Nodule (a growth of abnormal tissue)
Oropharyngeal pain

male:

Abnormal behaviour
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cardiac failure congestive
Diarrhoea
Drug ineffective
Hyperlipidaemia (presence of excess lipids in the blood)
International normalised ratio increased
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Chronic kidney disease
Acute myocardial infarction (acute heart attack)

What are the common drug interactions of Coreg Cr and Simvastatin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Accident at work
Loss of consciousness
Partial seizures (seizures which affect only a part of the brain at onset)
Anaemia (lack of blood)
Drug effect decreased
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Sinusitis (inflammation of sinus)

50-59:

Diabetic foot
Wound infection staphylococcal
Chronic kidney disease
Drug hypersensitivity
Peripheral swelling
Acute myocardial infarction (acute heart attack)
Drug administration error
Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)
Heart rate increased

60+:

Asthenia (weakness)
Abnormal behaviour
Weight decreased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Dementia (madness)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Fall
Hyperlipidaemia (presence of excess lipids in the blood)
Injection site atrophy (injection site wasting or decreasing in size of a body organ, tissue, or part)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 16.07%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 14.29%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 10.71%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 7.14%
Multiple Myeloma (cancer of the plasma cells): 4 people, 7.14%
Stable Angina (a constant chest pain): 3 people, 5.36%
Gout (uric acid crystals building up in the body): 3 people, 5.36%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 5.36%

* Approximation only. Some reports may have incomplete information.

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