Coreg and Rubraca drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Coreg (carvedilol) and Rubraca (rucaparib camsylate). Common drug interactions include carbohydrate antigen 125 increased among females.
The phase IV clinical study analyzes what interactions people have when they take Coreg and Rubraca. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.
What is Coreg?
Coreg has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 49,583 Coreg users. Check the latest studies of Coreg.
What is Rubraca?
Rubraca has active ingredients of rucaparib camsylate. eHealthMe is studying from 10,770 Rubraca users. Check the latest studies of Rubraca.
15 people who take Coreg and Rubraca together, and have interactions are studied.
What are the common drug interactions of Coreg and Rubraca, by gender? *:
female:
- Carbohydrate antigen 125 increased
- White blood cell count decreased
- Adverse event
- Arthralgia (joint pain)
- Gingival bleeding (bleeding gums)
- Hot flush (sudden feelings of heat)
- Insomnia (sleeplessness)
- Malaise (a feeling of general discomfort or uneasiness)
- Metastases to lymph nodes (cancer spreads to lymph node)
- Platelet count decreased
male:
n/a
What are the common drug interactions of Coreg and Rubraca, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Lung neoplasm malignant (cancer tumour of lung)
50-59:
- Febrile neutropenia (fever with reduced white blood cells)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Skin infection
60+:
- Carbohydrate antigen 125 increased
- White blood cell count decreased
- Adverse event
- Arthralgia (joint pain)
- Gingival bleeding (bleeding gums)
- Hot flush (sudden feelings of heat)
- Insomnia (sleeplessness)
- Malaise (a feeling of general discomfort or uneasiness)
- Metastases to lymph nodes (cancer spreads to lymph node)
- Platelet count decreased
What are the existing conditions these people have? *
- Ovarian Cancer (cancer of ovary): 8 people, 53.33%
- Nausea (feeling of having an urge to vomit): 4 people, 26.67%
- Fallopian Tube Cancer (cancer of fallopian tube): 3 people, 20.00%
- Pain: 2 people, 13.33%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 13.33%
- Ovarian Cancer Stage Iv: 1 person, 6.67%
- Ovarian Cancer Recurrent (reoccurrence of ovary cancer): 1 person, 6.67%
- Migraine (headache): 1 person, 6.67%
- Lung Cancer - Non-Small Cell (lung cancer): 1 person, 6.67%
- Insomnia (sleeplessness): 1 person, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Coreg and Rubraca?
- Personalize this study to your gender, age, symptoms and drugs
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Coreg and Rubraca:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Coreg:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Rubraca:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Coreg and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Rubraca and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
- Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
- Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
- Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on carvedilol and rucaparib camsylate (the active ingredients of Coreg and Rubraca, respectively), and Coreg and Rubraca (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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