Cosentyx and Cipro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cosentyx (secukinumab) and Cipro (ciprofloxacin hydrochloride). Common drug interactions include malaise among females and pruritus among males.

The phase IV clinical study analyzes what interactions people have when they take Cosentyx and Cipro. It is created by eHealthMe based on reports of 63 people who take the same drugs from the FDA, and is updated regularly.

What is Cosentyx?

Cosentyx has active ingredients of secukinumab. It is often used in psoriatic arthritis. eHealthMe is studying from 187,247 Cosentyx users. Check the latest studies of Cosentyx.

What is Cipro?

Cipro has active ingredients of ciprofloxacin hydrochloride. It is often used in urinary tract infection. eHealthMe is studying from 35,126 Cipro users. Check the latest studies of Cipro.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 24, 2026

63 people who take Cosentyx and Cipro together, and have interactions are studied.

Cosentyx and Cipro drug interactions.

What are the common drug interactions of Cosentyx and Cipro, by gender? *:

female:

  1. Malaise (a feeling of general discomfort or uneasiness)
  2. Abdominal discomfort
  3. Abdominal pain upper
  4. Bowel movement irregularity
  5. Cough
  6. Dysuria (painful or difficult urination)
  7. Ear pruritus (pruritus or itching is ""the unpleasant skin sensation that frequently provokes scratching"" in ear)
  8. Eye irritation
  9. Eye pruritus (eye itching)
  10. Fatigue (feeling of tiredness)

male:

  1. Pruritus (severe itching of the skin)
  2. Abdominal discomfort
  3. Pain
  4. Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
  5. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  6. Arthralgia (joint pain)
  7. C-reactive protein increased
  8. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  9. Upper respiratory tract infection
  10. Anti-cyclic citrullinated peptide antibody positive

What are the common drug interactions of Cosentyx and Cipro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Accident at work
  2. Nerve injury

30-39:

  1. Ankylosing spondylitis (type of arthritis affecting the spine)

40-49:

  1. Nausea (feeling of having an urge to vomit)
  2. Diarrhoea
  3. Pyrexia (fever)
  4. Drug ineffective
  5. Psoriasis (immune-mediated disease that affects the skin)
  6. Arthralgia (joint pain)
  7. Back pain
  8. Abdominal discomfort
  9. Abdominal pain upper
  10. Bowel movement irregularity

50-59:

  1. Bone erosion
  2. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  3. Diarrhoea
  4. Drug hypersensitivity
  5. Drug ineffective
  6. Drug intolerance (drug sensitivity)
  7. Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
  8. Dyspepsia (indigestion)
  9. Gastrointestinal infection (infection of stomach and intestine)
  10. Hand deformity

60+:

  1. Nausea (feeling of having an urge to vomit)
  2. Psoriasis (immune-mediated disease that affects the skin)
  3. Post procedural haemorrhage (post procedural bleeding)
  4. Sexual dysfunction (difficulty experienced by an individual or a couple during any stage of a normal sexual activity)
  5. Arthralgia (joint pain)
  6. Drug ineffective
  7. Pyrexia (fever)
  8. Cough
  9. Dysuria (painful or difficult urination)
  10. Ear pruritus (pruritus or itching is ""the unpleasant skin sensation that frequently provokes scratching"" in ear)

What are the existing conditions these people have? *

  1. Psoriasis (immune-mediated disease that affects the skin): 52 people, 82.54%
  2. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 26 people, 41.27%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 16 people, 25.40%
  4. Nausea (feeling of having an urge to vomit): 9 people, 14.29%
  5. Ankylosing Spondylitis (type of arthritis affecting the spine): 5 people, 7.94%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cosentyx and Cipro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cosentyx:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cipro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cosentyx and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cipro and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on secukinumab and ciprofloxacin hydrochloride (the active ingredients of Cosentyx and Cipro, respectively), and Cosentyx and Cipro (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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