Cosmegen and Dexamethasone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cosmegen (dactinomycin) and Dexamethasone (dexamethasone). Common drug interactions include device expulsion among females and febrile neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Cosmegen and Dexamethasone. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Cosmegen?

Cosmegen has active ingredients of dactinomycin. eHealthMe is studying from 937 Cosmegen users. Check the latest studies of Cosmegen.

What is Dexamethasone?

Dexamethasone has active ingredients of dexamethasone. It is often used in multiple myeloma. eHealthMe is studying from 161,927 Dexamethasone users. Check the latest studies of Dexamethasone.

On Jul, 11, 2026

20 people who take Cosmegen and Dexamethasone together, and have interactions are studied.

Cosmegen and Dexamethasone drug interactions.

What are the common drug interactions of Cosmegen and Dexamethasone, by gender? *:

female:

Device expulsion
Fatigue (feeling of tiredness)
Feeding disorder (when children refuse to eat certain food groups)
Gestational trophoblastic tumour
Haemoglobin decreased
Leukopenia (less number of white blood cells in blood)
Nausea (feeling of having an urge to vomit)
Oral pain
Pallor
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

male:

Febrile neutropenia (fever with reduced white blood cells)
Hypophagia (reduced food intake)
Pleural effusion (water on the lungs)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Inappropriate antidiuretic hormone secretion

What are the common drug interactions of Cosmegen and Dexamethasone, by age (0-1 to 60+)? *:

0-1:

Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)

2-9:

Feeding disorder (when children refuse to eat certain food groups)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Inappropriate antidiuretic hormone secretion
Leukopenia (less number of white blood cells in blood)
Nausea (feeling of having an urge to vomit)
Oral pain
Pallor
Vomiting
Febrile neutropenia (fever with reduced white blood cells)

10-19:

Febrile neutropenia (fever with reduced white blood cells)
Haemoglobin decreased
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Platelet count decreased
Presyncope
Stomatitis (inflammation of mucous membrane of mouth)
White blood cell count decreased

20-29:

Gestational trophoblastic tumour
Tumour marker increased

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Rhabdomyosarcoma (cancer of the bone, soft tissues, or connective tissue (e.g., tendon or cartilage)): 7 people, 35.00%
Sarcoma (rare cancers that develop in the muscle, bone, nerves, cartilage, tendons, blood vessels and the fatty and fibrous tissues): 5 people, 25.00%
Neoplasm Malignant (cancer tumour): 3 people, 15.00%
Wilms Tumor (cancer of the kidneys that typically occurs in children): 2 people, 10.00%
Nausea (feeling of having an urge to vomit): 2 people, 10.00%
Headache (pain in head): 1 person, 5.00%
Gestational Trophoblastic Tumor: 1 person, 5.00%
Ewing's Sarcoma (malignant small, round, blue cell tumour): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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