Cozaar and Uptravi drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cozaar (losartan potassium) and Uptravi (selexipag). Common drug interactions include peripheral swelling among females and arrhythmia among males.

The phase IV clinical study analyzes what interactions people have when they take Cozaar and Uptravi. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Cozaar?

Cozaar has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 45,124 Cozaar users. Check the latest studies of Cozaar.

What is Uptravi?

Uptravi has active ingredients of selexipag. eHealthMe is studying from 26,576 Uptravi users. Check the latest studies of Uptravi.

On Jul, 18, 2026

41 people who take Cozaar and Uptravi together, and have interactions are studied.

What are the common drug interactions of Cozaar and Uptravi, by gender? *:

female:

Peripheral swelling
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Back pain
Fatigue (feeling of tiredness)
Productive cough
Anaemia (lack of blood)
Blood creatinine increased
Flushing (the warm, red condition of human skin)
Dyspnoea exertional (breathlessness or shortness of breath)
Pulmonary hypertension (increase in blood pressure in the lung artery)

male:

Arrhythmia (irregular heartbeat)
Dyspnoea (difficult or laboured respiration)
Right ventricular failure (right half of the heart fails to work)

What are the common drug interactions of Cozaar and Uptravi, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Arrhythmia (irregular heartbeat)
Dyspnoea (difficult or laboured respiration)
Right ventricular failure (right half of the heart fails to work)

20-29:

n/a

30-39:

Back pain
Cardiac arrest
Fall
Loss of consciousness

40-49:

Diarrhoea
Headache (pain in head)
Vomiting
Dry mouth
Dysgeusia (disorder of the sense of taste)
Fatigue (feeling of tiredness)
Hypotension (abnormally low blood pressure)
Myalgia (muscle pain)
Anaemia (lack of blood)
Blood potassium decreased

50-59:

Headache (pain in head)
Diarrhoea
Flushing (the warm, red condition of human skin)
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Pain in extremity
Peripheral swelling
Breast cancer
Weight decreased
Abdominal distension

60+:

Headache (pain in head)
Diarrhoea
Decreased appetite
Fluid retention (an abnormal accumulation of fluid in the blood)
Flushing (the warm, red condition of human skin)
Myalgia (muscle pain)
Oedema (fluid collection in tissue)
Pain in extremity
Peripheral swelling
Procedural pain

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 27 people, 65.85%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 7 people, 17.07%

* Approximation only. Some reports may have incomplete information.

Do you take Cozaar and Uptravi?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously