Creatine and Ademetionine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Creatine (creatine) and Ademetionine (same). Common drug interactions include ear congestion among females and blood creatine phosphokinase increased among males.

The phase IV clinical study analyzes what interactions people have when they take Creatine and Ademetionine. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Creatine?

Creatine has active ingredients of creatine. It is often used in muscle mass. eHealthMe is studying from 1,390 Creatine users. Check the latest studies of Creatine.

What is Ademetionine?

Ademetionine has active ingredients of same. eHealthMe is studying from 748 Ademetionine users. Check the latest studies of Ademetionine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 16, 2026

11 people who take Creatine and Ademetionine together, and have interactions are studied.

Creatine and Ademetionine drug interactions.

What are the common drug interactions of Creatine and Ademetionine, by gender? *:

female:

Ear congestion
Eructation (release of gas from the digestive tract)
Haematuria (presence of blood in urine)
Headache (pain in head)
Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)
Lymphadenopathy (disease or enlargement of lymph nodes)
Nightmare (unpleasant dream)
Pain in extremity
Paranasal sinus hypersecretion
Skin exfoliation (removal of the oldest dead skin cells)

male:

Blood creatine phosphokinase increased
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Jugular vein thrombosis (clot in jugular vein)
Subclavian vein thrombosis (abnormal condition in which a clot develops within the subclavian or axillary vein)
Anaemia (lack of blood)
Blood urine present
Carotid artery thrombosis (blood clot in carotid artery)
Decreased appetite
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Frequent bowel movements

What are the common drug interactions of Creatine and Ademetionine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Asthenia (weakness)
Axillary vein thrombosis (formation of a blood clot in axillary vein)
Blood albumin decreased
Bone marrow failure
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diarrhoea
Dizziness
Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)
Jugular vein thrombosis (clot in jugular vein)
Subclavian vein thrombosis (abnormal condition in which a clot develops within the subclavian or axillary vein)

50-59:

Anaemia (lack of blood)
Blood urine present
Decreased appetite
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diarrhoea
Dizziness
Frequent bowel movements
Herpes virus infection
Hyperhidrosis (abnormally increased sweating)
Loss of consciousness

60+:

Blood creatine phosphokinase increased
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Paranasal sinus hypersecretion
Skin exfoliation (removal of the oldest dead skin cells)
Urinary tract infection
Ear congestion
Eructation (release of gas from the digestive tract)
Haematuria (presence of blood in urine)
Headache (pain in head)
Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)

What are the existing conditions these people have? *

Urination - Excessive Volume: 6 people, 54.55%
Hyperglycemia (high blood sugar): 4 people, 36.36%
Productive Cough: 4 people, 36.36%
Conjunctivitis (pink eye): 4 people, 36.36%
Pericardial Effusion (fluid around the heart): 4 people, 36.36%
Cough: 4 people, 36.36%
Lung Cancer - Non-Small Cell (lung cancer): 4 people, 36.36%
Ligament Sprain (ligament stretched): 4 people, 36.36%
Joint Pain: 4 people, 36.36%
Venous Thrombosis (blood clot (thrombus) that forms within a vein): 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

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