Creon and Astelin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Creon (pancrelipase (amylase;lipase;protease)) and Astelin (azelastine hydrochloride). Common drug interactions include infective pulmonary exacerbation of cystic fibrosis among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Creon and Astelin. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Creon?

Creon has active ingredients of pancrelipase (amylase;lipase;protease). It is often used in pancreatitis. eHealthMe is studying from 29,489 Creon users. Check the latest studies of Creon.

What is Astelin?

Astelin has active ingredients of azelastine hydrochloride. It is often used in allergies. eHealthMe is studying from 5,538 Astelin users. Check the latest studies of Astelin.

On Jul, 12, 2026

34 people who take Creon and Astelin together, and have interactions are studied.

What are the common drug interactions of Creon and Astelin, by gender? *:

female:

Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Blood albumin decreased
Blood glucose decreased
Blood glucose increased
Dyspnoea (difficult or laboured respiration)
Gastritis (inflammation of stomach)
Hepatic infection
Hepatitis cholestatic (flow of bile from the liver is slowed or blocked)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Muscle spasms (muscle contraction)

male:

Pain
Cholangitis (infection of the bile duct)
Pancreatic neoplasm (pancreatic tumour)
Pancreatic neuroendocrine tumour
Tremor (trembling or shaking movements in one or more parts of your body)
Vision blurred
Abnormal behaviour
Acute respiratory distress syndrome
Acute sinusitis
Aggression

What are the common drug interactions of Creon and Astelin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Abnormal behaviour
Aggression
Bronchial hyperreactivity
Delayed puberty
Epiphyses delayed fusion
Flatulence (flatus expelled through the anus)
Growth hormone deficiency
Growth retardation (delayed growth)
Nasal oedema (fluid collection in nose)

20-29:

Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Acute sinusitis
Dizziness
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Influenza like illness
Nausea (feeling of having an urge to vomit)
Pulmonary function test decreased

30-39:

Abdominal pain
Back pain
Chest discomfort
Dysphagia (a condition in which swallowing is difficult or painful)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)

40-49:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Dysarthria (speech disorder)
Fatigue (feeling of tiredness)
Pain
Tremor (trembling or shaking movements in one or more parts of your body)
Vision blurred
Cystic fibrosis (disease of the secretary glands)
Dyspnoea (difficult or laboured respiration)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Weight decreased

50-59:

n/a

60+:

Cholangitis (infection of the bile duct)
Enterococcal bacteraemia (presence of bacteria lactic acid in the blood)
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Respiratory tract congestion (blockage on respiratory system)
Upper respiratory tract infection
Obstruction gastric (obstruction in stomach)
Vomiting
Asthenia (weakness)
Blood pressure increased

What are the existing conditions these people have? *

Cystic Fibrosis (disease of the secretary glands): 12 people, 35.29%
Nausea (feeling of having an urge to vomit): 8 people, 23.53%
Constipation: 7 people, 20.59%
Nausea And Vomiting: 6 people, 17.65%
Stress And Anxiety: 6 people, 17.65%
Cough: 4 people, 11.76%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 11.76%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 8.82%
Cystic Fibrosis Lung (fibrosis with cyst in the lung): 3 people, 8.82%
Immunodeficiency Common Variable: 3 people, 8.82%

* Approximation only. Some reports may have incomplete information.

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