Crestor and Aptiom drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Crestor (rosuvastatin calcium) and Aptiom (eslicarbazepine acetate). Common drug interactions include seizure among females and abnormal behaviour among males.

The phase IV clinical study analyzes what interactions people have when they take Crestor and Aptiom. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Crestor?

Crestor has active ingredients of rosuvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 149,761 Crestor users. Check the latest studies of Crestor.

What is Aptiom?

Aptiom has active ingredients of eslicarbazepine acetate. eHealthMe is studying from 2,404 Aptiom users. Check the latest studies of Aptiom.



On Jul, 20, 2026

18 people who take Crestor and Aptiom together, and have interactions are studied.

Crestor and Aptiom drug interactions.

What are the common drug interactions of Crestor and Aptiom, by gender? *:

female:

  1. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  2. Contusion (a type of hematoma of tissue in which capillaries)
  3. Fall
  4. Nausea (feeling of having an urge to vomit)
  5. Dizziness postural
  6. Constipation
  7. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  8. Somnolence (a state of near-sleep, a strong desire for sleep)
  9. Migraine (headache)
  10. Arthralgia (joint pain)

male:

  1. Abnormal behaviour
  2. Agitation (state of anxiety or nervous excitement)
  3. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  4. Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
  5. Psychotic disorder
  6. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  7. Somnolence (a state of near-sleep, a strong desire for sleep)
  8. Speech disorder
  9. Tremor (trembling or shaking movements in one or more parts of your body)
  10. Anger

What are the common drug interactions of Crestor and Aptiom, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Drug ineffective
  2. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  3. Pain
  4. Dizziness
  5. Nausea (feeling of having an urge to vomit)
  6. Therapeutic response unexpected
  7. Aphasia (damage to the parts of the brain that control language)
  8. Balance disorder
  9. Blood pressure decreased
  10. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)

60+:

  1. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  2. Contusion (a type of hematoma of tissue in which capillaries)
  3. Mass
  4. Nausea (feeling of having an urge to vomit)
  5. Chest discomfort
  6. Low density lipoprotein increased (cholesterol increased in blood)
  7. Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
  8. Migraine (headache)
  9. Rash
  10. Skin discolouration (change of skin colour)

What are the existing conditions these people have? *

  1. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 4 people, 22.22%
  2. High Blood Pressure: 4 people, 22.22%
  3. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 16.67%
  4. Partial Seizures (seizures which affect only a part of the brain at onset): 3 people, 16.67%
  5. Migraine (headache): 3 people, 16.67%
  6. Thyroid Diseases: 2 people, 11.11%
  7. Hypotension (abnormally low blood pressure): 2 people, 11.11%
  8. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 2 people, 11.11%
  9. Head Injury: 2 people, 11.11%
  10. Asthma: 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Crestor and Aptiom:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Crestor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Aptiom:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Crestor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aptiom and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on rosuvastatin calcium and eslicarbazepine acetate (the active ingredients of Crestor and Aptiom, respectively), and Crestor and Aptiom (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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