Crestor and Pyridium drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Crestor (rosuvastatin calcium) and Pyridium (phenazopyridine hydrochloride). Common drug interactions include muscular weakness among females and anaemia among males.
The phase IV clinical study analyzes what interactions people have when they take Crestor and Pyridium. It is created by eHealthMe based on reports of 86 people who take the same drugs from the FDA, and is updated regularly.
What is Crestor?
Crestor has active ingredients of rosuvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 149,761 Crestor users. Check the latest studies of Crestor.
What is Pyridium?
Pyridium has active ingredients of phenazopyridine hydrochloride. It is often used in urinary tract infection. eHealthMe is studying from 1,841 Pyridium users. Check the latest studies of Pyridium.
86 people who take Crestor and Pyridium together, and have interactions are studied.

What are the common drug interactions of Crestor and Pyridium, by gender? *:
female:
- Muscular weakness (muscle weakness)
- Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
- Pain
- Renal disorder (kidney disease)
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Abdominal discomfort
- Adverse drug reaction
- Drug ineffective
- Dyspnoea (difficult or laboured respiration)
- Malaise (a feeling of general discomfort or uneasiness)
male:
- Anaemia (lack of blood)
- Bladder disorder
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Headache (pain in head)
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Nausea (feeling of having an urge to vomit)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
- Bladder transitional cell carcinoma recurrent (types of bladder cancer-recurrent)
What are the common drug interactions of Crestor and Pyridium, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Migraine (headache)
- Mood swings (an extreme or rapid change in mood)
- Sinus disorder (disease of sinus)
- Sinusitis (inflammation of sinus)
- Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
- Vomiting
- Pneumonia
- Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
- Extrasystoles
- Fall
60+:
- Chronic kidney disease
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Nausea (feeling of having an urge to vomit)
- Anaemia (lack of blood)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Bone pain
- Burning sensation
- Drug hypersensitivity
- Dyspepsia (indigestion)
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 26 people, 30.23%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 20 people, 23.26%
- Pain: 14 people, 16.28%
- High Blood Pressure: 14 people, 16.28%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 13 people, 15.12%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 12 people, 13.95%
- Stress And Anxiety: 8 people, 9.30%
- Type 2 Diabetes: 6 people, 6.98%
- Hyperlipidaemia (presence of excess lipids in the blood): 6 people, 6.98%
- Fibromyalgia (a long-term condition which causes pain all over the body): 6 people, 6.98%
* Approximation only. Some reports may have incomplete information.
Do you take Crestor and Pyridium?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Crestor and Pyridium:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Crestor:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Pyridium:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Crestor and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pyridium and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on rosuvastatin calcium and phenazopyridine hydrochloride (the active ingredients of Crestor and Pyridium, respectively), and Crestor and Pyridium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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