Cubicin and Morphine sulfate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cubicin (daptomycin) and Morphine sulfate (morphine sulfate). Common drug interactions include blood creatine phosphokinase increased among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Cubicin and Morphine sulfate. It is created by eHealthMe based on reports of 69 people who take the same drugs from the FDA, and is updated regularly.

What is Cubicin?

Cubicin has active ingredients of daptomycin. It is often used in infection. eHealthMe is studying from 7,991 Cubicin users. Check the latest studies of Cubicin.

What is Morphine sulfate?

Morphine sulfate has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 87,262 Morphine sulfate users. Check the latest studies of Morphine sulfate.

On Aug, 09, 2026

69 people who take Cubicin and Morphine sulfate together, and have interactions are studied.

Cubicin and Morphine sulfate drug interactions.

What are the common drug interactions of Cubicin and Morphine Sulfate, by gender? *:

female:

Blood creatine phosphokinase increased
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Heart rate irregular
Disease progression
Drug hypersensitivity
Sepsis (a severe blood infection that can lead to organ failure and death)
Rash
Diarrhoea
Incoherent (talking in a confused and unclear way)

male:

Pyrexia (fever)
Multiple myeloma (cancer of the plasma cells)
Cerebral artery embolism (sudden blocking of an artery by a clot or foreign material)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Chronic kidney disease
Coma (state of unconsciousness lasting more than six hours)
Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Febrile neutropenia (fever with reduced white blood cells)
Hepatitis (inflammation of the liver)
Intestinal haemorrhage (bleeding from intestine)

What are the common drug interactions of Cubicin and Morphine Sulfate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Sepsis (a severe blood infection that can lead to organ failure and death)

20-29:

n/a

30-39:

Aortic valve disease
Cardiac failure congestive
Cardiac valve disease (heart valve disease)
Cellulitis (infection under the skin)
Cerebral artery embolism (sudden blocking of an artery by a clot or foreign material)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Chronic kidney disease
Coma (state of unconsciousness lasting more than six hours)
Eosinophilia (eosinophil count in the peripheral blood exceeds)
Kidney transplant rejection

40-49:

Pyrexia (fever)
Multiple myeloma (cancer of the plasma cells)
Nausea (feeling of having an urge to vomit)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Pulmonary haemorrhage (acute bleeding from the lung)
Thrombocytopenia (decrease of platelets in blood)
Hepatitis (inflammation of the liver)

50-59:

Diarrhoea
Incoherent (talking in a confused and unclear way)
Ingrowing nail
Sepsis (a severe blood infection that can lead to organ failure and death)
Chills (felling of cold)
Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Febrile neutropenia (fever with reduced white blood cells)
Headache (pain in head)
Infusion site extravasation (flow of (blood or lymph) from infusion site)
Injection site extravasation (flow of (blood or lymph) from injection site)

60+:

Blood creatine phosphokinase increased
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Rash
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Diarrhoea
Incoherent (talking in a confused and unclear way)
Ingrowing nail
Pruritus (severe itching of the skin)
Sepsis (a severe blood infection that can lead to organ failure and death)
Anaemia (lack of blood)

What are the existing conditions these people have? *

Arthritis Infective (purulent invasion of a joint by an infectious agent which produces arthritis): 37 people, 53.62%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 13 people, 18.84%
Neuropathy Peripheral (surface nerve damage): 4 people, 5.80%

* Approximation only. Some reports may have incomplete information.

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