Curcumin and Lupron drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Curcumin (turmeric) and Lupron (leuprolide acetate). Common drug interactions include weight decreased among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Curcumin and Lupron. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Curcumin?

Curcumin has active ingredients of turmeric. It is often used in inflammation. eHealthMe is studying from 3,677 Curcumin users. Check the latest studies of Curcumin.

What is Lupron?

Lupron has active ingredients of leuprolide acetate. It is often used in endometriosis. eHealthMe is studying from 42,122 Lupron users. Check the latest studies of Lupron.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

27 people who take Curcumin and Lupron together, and have interactions are studied.

What are the common drug interactions of Curcumin and Lupron, by gender? *:

female:

Weight decreased
Hot flush (sudden feelings of heat)
Alopecia (absence of hair from areas of the body)
Drug ineffective
Ovarian cyst (fluid filled sac of the ovary)
Pelvic pain
Sleep disorder
Fatigue (feeling of tiredness)
Headache (pain in head)
Pain

male:

Fatigue (feeling of tiredness)
Diarrhoea
Micturition urgency (urgency to pass the urine)
Pain
Vertigo
Adverse drug reaction
Coeliac artery stenosis (abnormal narrowing of coeliac artery)
Metastases to bone (cancer spreads to bone)
Normochromic normocytic anaemia (forms of anaemia in which the average size and haemoglobin content of the red blood cells are within normal limits)
Presyncope

What are the common drug interactions of Curcumin and Lupron, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Dizziness
Weight decreased

20-29:

n/a

30-39:

Night sweats (sweating in night)
Pain
Asthenia (weakness)
Bronchial obstruction (blockage of the breathing passages to the lungs)
Chest pain
Fatigue (feeling of tiredness)
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
Granuloma (a small area of inflammation due to tissue injury)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Headache (pain in head)

40-49:

Abdominal distension
Abdominal pain upper
Fatigue (feeling of tiredness)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Genital disorder female (diseases of female genital tract)
Headache (pain in head)
Hot flush (sudden feelings of heat)
Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
Insomnia (sleeplessness)
Irritable bowel syndrome

50-59:

Anaemia (lack of blood)
Arthralgia (joint pain)
Blood cholesterol increased
Breast enlargement
Fatigue (feeling of tiredness)
Hot flush (sudden feelings of heat)
Loss of libido (loss of sexual urge)
Sexual dysfunction (difficulty experienced by an individual or a couple during any stage of a normal sexual activity)
Visual impairment
Weight increased

60+:

Fatigue (feeling of tiredness)
Bone pain
Vertigo
Adverse drug reaction
Coeliac artery stenosis (abnormal narrowing of coeliac artery)
Metastases to bone (cancer spreads to bone)
Normochromic normocytic anaemia (forms of anaemia in which the average size and haemoglobin content of the red blood cells are within normal limits)
Presyncope
Thrombocytopenia (decrease of platelets in blood)
Vomiting

What are the existing conditions these people have? *

Prostate Cancer: 13 people, 48.15%
Prostate Cancer Metastatic: 5 people, 18.52%
Prostatic Specific Antigen Increased: 3 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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