Cyanocobalamin and Actonel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cyanocobalamin (cyanocobalamin) and Actonel (risedronate sodium). Common drug interactions include pain among females and abscess soft tissue among males.

The phase IV clinical study analyzes what interactions people have when they take Cyanocobalamin and Actonel. It is created by eHealthMe based on reports of 75 people who take the same drugs from the FDA, and is updated regularly.

What is Cyanocobalamin?

Cyanocobalamin has active ingredients of cyanocobalamin. It is often used in vitamin b12 deficiency. eHealthMe is studying from 14,651 Cyanocobalamin users. Check the latest studies of Cyanocobalamin.

What is Actonel?

Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 29,369 Actonel users. Check the latest studies of Actonel.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

75 people who take Cyanocobalamin and Actonel together, and have interactions are studied.

Cyanocobalamin and Actonel drug interactions.

What are the common drug interactions of Cyanocobalamin and Actonel, by gender? *:

female:

Pain
Rash pruritic (redness with itching)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Vomiting
Hypersensitivity
Weight decreased
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Arthropathy
Back pain

male:

Abscess soft tissue (soft tissue abscesses)
Comminuted fracture (bone has broken into several pieces)
Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
Tibia fracture (fracture of lower leg bone)
Pleural effusion (water on the lungs)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood alkaline phosphatase increased
Blood bilirubin increased
Blood lactate dehydrogenase increased

What are the common drug interactions of Cyanocobalamin and Actonel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cardiac failure
Drug intolerance (drug sensitivity)
Dysphagia (a condition in which swallowing is difficult or painful)
Vomiting

30-39:

Depression
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Suicide attempt

40-49:

Blood pressure systolic increased
Pneumonia
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Blood pressure increased
Cystitis (inflammation of the wall of the bladder)
Pyrexia (fever)
Sinusitis (inflammation of sinus)
Anaemia (lack of blood)
Asthma
Blood cholesterol increased

50-59:

Infection
Insomnia (sleeplessness)
Joint range of motion decreased (disease of joint movement)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Nodule (a growth of abnormal tissue)
Pain in extremity
Peripheral swelling
Pneumonia
Psoriasis (immune-mediated disease that affects the skin)
Somnolence (a state of near-sleep, a strong desire for sleep)

60+:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood bilirubin increased
Dysphagia (a condition in which swallowing is difficult or painful)
Malaise (a feeling of general discomfort or uneasiness)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Weight decreased
Blood glucose increased
C-reactive protein increased
Platelet count decreased

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 32 people, 42.67%
Gastritis (inflammation of stomach): 15 people, 20.00%
Pain: 10 people, 13.33%
Gastric Disorder (disease of stomach): 9 people, 12.00%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 9 people, 12.00%
Nausea (feeling of having an urge to vomit): 8 people, 10.67%
Hyperlipidaemia (presence of excess lipids in the blood): 8 people, 10.67%
Neuralgia (pain in one or more nerves): 7 people, 9.33%
Ankylosing Spondylitis (type of arthritis affecting the spine): 7 people, 9.33%
Gastric Ulcer (stomach ulcer): 6 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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