Cytomel and Cevimeline drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Cytomel (liothyronine sodium) and Cevimeline (cevimeline hydrochloride). Common drug interactions include malaise among females.
The phase IV clinical study analyzes what interactions people have when they take Cytomel and Cevimeline. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Cytomel?
Cytomel has active ingredients of liothyronine sodium. It is often used in hypothyroidism. eHealthMe is studying from 7,595 Cytomel users. Check the latest studies of Cytomel.
What is Cevimeline?
Cevimeline has active ingredients of cevimeline hydrochloride. It is often used in sjogren syndrome. eHealthMe is studying from 1,480 Cevimeline users. Check the latest studies of Cevimeline.
16 people who take Cytomel and Cevimeline together, and have interactions are studied.

What are the common drug interactions of Cytomel and Cevimeline, by gender? *:
female:
- Malaise (a feeling of general discomfort or uneasiness)
- Postural orthostatic tachycardia syndrome (abnormal increase in heart rate on becoming upright)
- Impaired gastric emptying
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Surgery
- Anaemia (lack of blood)
- Cardiomegaly (increased size of heart than normal)
- Dyslexia (disorders that involve difficulty in learning to read or interpret words, letters, and other symbols)
- Hereditary angioedema (recurrent episodes of severe swelling)
male:
n/a
What are the common drug interactions of Cytomel and Cevimeline, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Aphonia (inability to produce voice)
- Cough
- Ear infection
- Ear pain
- Laryngitis (inflammation of the larynx)
- Oropharyngeal pain
- Sinus congestion (blockage of sinus)
- Sinusitis (inflammation of sinus)
40-49:
- Asthma
- Dyspnoea (difficult or laboured respiration)
- Skin reaction
- Stiff person syndrome
- Weight decreased
- Abdominal discomfort
- Peripheral swelling
- Swelling face
- Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
- Erythema (redness of the skin)
50-59:
n/a
60+:
n/a
What are the existing conditions these people have? *
- Immune System Disorder: 8 people, 50.00%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 12.50%
- Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 12.50%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 12.50%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 6.25%
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 6.25%
- Psoriasis (immune-mediated disease that affects the skin): 1 person, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Cytomel and Cevimeline?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Cytomel (7,595 reports)
- Cevimeline (1,480 reports)
Browse all drug interactions of Cytomel and Cevimeline:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cytomel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cevimeline:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cytomel and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cevimeline and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on liothyronine sodium and cevimeline hydrochloride (the active ingredients of Cytomel and Cevimeline, respectively), and Cytomel and Cevimeline (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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