Cytosar-u and Mesna drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cytosar-u (cytarabine) and Mesna (mesna). Common drug interactions include diarrhoea among females and altered state of consciousness among males.

The phase IV clinical study analyzes what interactions people have when they take Cytosar-u and Mesna. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Cytosar-u?

Cytosar-u has active ingredients of cytarabine. eHealthMe is studying from 586 Cytosar-u users. Check the latest studies of Cytosar-u.

What is Mesna?

Mesna has active ingredients of mesna. eHealthMe is studying from 9,647 Mesna users. Check the latest studies of Mesna.



On Jul, 13, 2026

19 people who take Cytosar-u and Mesna together, and have interactions are studied.

Cytosar-u and Mesna drug interactions.

What are the common drug interactions of Cytosar-U and Mesna, by gender? *:

female:

  1. Diarrhoea
  2. Dizziness
  3. Drug abuse
  4. Eosinophilia (eosinophil count in the peripheral blood exceeds)
  5. Fall
  6. Fatigue (feeling of tiredness)
  7. Febrile neutropenia (fever with reduced white blood cells)
  8. Headache (pain in head)
  9. Hodgkin's disease (cancer originating from white blood cells)
  10. Inflammation

male:

  1. Altered state of consciousness (altered state of mind)
  2. Circulatory collapse
  3. Mucosal inflammation (infection of mucous membrane)
  4. Nausea (feeling of having an urge to vomit)
  5. Alanine aminotransferase increased
  6. Anaemia (lack of blood)
  7. Anxiety
  8. Aspartate aminotransferase increased
  9. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  10. Dizziness

What are the common drug interactions of Cytosar-U and Mesna, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Guillain barre syndrome (the body's immune system attacks its peripheral nervous system)
  2. Multi-organ failure (multisystem organ failure)
  3. Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis)
  4. Cardiac tamponade (fluid accumulates in heart covering)
  5. Difficulty in walking
  6. Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
  7. Parainfluenzae virus infection
  8. Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously)
  9. Respiratory failure (excl neonatal) (inadequate gas exchange by the respiratory system(excluding neonatal))

20-29:

  1. Stomatitis (inflammation of mucous membrane of mouth)
  2. Subcutaneous nodule
  3. Blood glucose increased
  4. Blood urea nitrogen/creatinine ratio increased
  5. Drug abuse
  6. Laceration (tearing of soft body tissue)
  7. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  8. Palpitations (feelings or sensations that your heart is pounding or racing)
  9. Alanine aminotransferase increased
  10. Anaemia (lack of blood)

30-39:

n/a

40-49:

n/a

50-59:

  1. Bladder fibrosis (formation of excess fibrous connective tissue in bladder)
  2. Cerebellar ataxia (loss of coordination)
  3. Haematuria (presence of blood in urine)
  4. Headache (pain in head)
  5. Hypotension (abnormally low blood pressure)
  6. Insomnia (sleeplessness)
  7. Oropharyngeal pain
  8. Syncope (loss of consciousness with an inability to maintain postural tone)
  9. Urinary bladder haemorrhage (urinary bladder bleeding)
  10. Chills (felling of cold)

60+:

  1. Altered state of consciousness (altered state of mind)
  2. Circulatory collapse
  3. Pneumonia
  4. Blood ph decreased
  5. Gamma-glutamyltransferase increased
  6. Haematocrit decreased
  7. Haemoglobin decreased
  8. Platelet count decreased
  9. Red blood cell count decreased

What are the existing conditions these people have? *

  1. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 6 people, 31.58%
  2. Fluid Retention (an abnormal accumulation of fluid in the blood): 5 people, 26.32%
  3. Nausea (feeling of having an urge to vomit): 4 people, 21.05%
  4. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 4 people, 21.05%
  5. Pain: 3 people, 15.79%
  6. Stress And Anxiety: 2 people, 10.53%
  7. Nausea And Vomiting: 2 people, 10.53%
  8. Gastric Ph Decreased: 2 people, 10.53%
  9. Gastric Disorder (disease of stomach): 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

Do you take Cytosar-u and Mesna?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cytosar-u and Mesna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cytosar-u:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Mesna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cytosar-u and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mesna and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cytarabine and mesna (the active ingredients of Cytosar-u and Mesna, respectively), and Cytosar-u and Mesna (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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