Crixivan and Naproxen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Crixivan (indinavir sulfate) and Naproxen (naproxen). Common drug interactions include neck pain among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Crixivan and Naproxen. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Crixivan?

Crixivan has active ingredients of indinavir sulfate. eHealthMe is studying from 6,312 Crixivan users. Check the latest studies of Crixivan.

What is Naproxen?

Naproxen has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 72,032 Naproxen users. Check the latest studies of Naproxen.



On Jul, 13, 2026

32 people who take Crixivan and Naproxen together, and have interactions are studied.

Crixivan and Naproxen drug interactions.

What are the common drug interactions of Crixivan and Naproxen, by gender? *:

female:

  1. Neck pain
  2. Rash generalised (rash on most of body parts)
  3. Upper limb fracture
  4. Abdominal distension
  5. Asthenia (weakness)
  6. Blood creatinine increased
  7. Blood urea increased
  8. Bone loss
  9. Calculus urinary (stone in urinary system)
  10. Decreased appetite

male:

  1. Anxiety
  2. Emotional distress
  3. Mobility decreased (ability to move is reduced)
  4. Bone loss
  5. Hand fracture
  6. Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema)
  7. Osteonecrosis (death of bone)
  8. Rib fracture
  9. Tooth loss
  10. Abdominal pain

What are the common drug interactions of Crixivan and Naproxen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Hand fracture
  2. Rib fracture
  3. Bone density decreased
  4. Foot fracture
  5. Gait disturbance
  6. Multiple fractures
  7. Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
  8. Osteopenia (a condition where bone mineral density is lower than normal)
  9. Osteoporosis (bones weak and more likely to break)
  10. Renal failure (kidney dysfunction)

40-49:

  1. Drug ineffective
  2. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  3. Dyspnoea (difficult or laboured respiration)
  4. Dyspnoea paroxysmal nocturnal (respiratory distress that awakens patients from sleep)
  5. Emotional distress
  6. Exostosis (formation of new bone on the surface of a bone)
  7. Eyelid ptosis (falling of the upper or lower eyelid)
  8. Flushing (the warm, red condition of human skin)
  9. Gingival swelling (gums swelling)
  10. Haematuria (presence of blood in urine)

50-59:

  1. Anxiety
  2. Emotional distress
  3. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  4. Arthralgia (joint pain)
  5. Chronic kidney disease
  6. Fatigue (feeling of tiredness)
  7. Mobility decreased (ability to move is reduced)
  8. Ascites (accumulation of fluid in the abdominal cavity)
  9. Bone density decreased
  10. Bone loss

60+:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Osteonecrosis (death of bone)
  4. Quality of life decreased
  5. Spinal compression fracture (fracture due to spinal compression on bone)
  6. Bone density decreased
  7. Emotional distress
  8. Osteopenia (a condition where bone mineral density is lower than normal)
  9. Osteoporosis (bones weak and more likely to break)
  10. Bone loss

What are the existing conditions these people have? *

  1. Hiv Infection: 22 people, 68.75%
  2. Infection: 4 people, 12.50%
  3. Stress And Anxiety: 3 people, 9.38%
  4. Hypersensitivity: 3 people, 9.38%
  5. Fungal Infection: 3 people, 9.38%
  6. Cough: 3 people, 9.38%
  7. Bacterial Infection: 3 people, 9.38%
  8. Rickets (softening of bones): 2 people, 6.25%
  9. Rashes (redness): 2 people, 6.25%
  10. High Blood Pressure: 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Crixivan and Naproxen?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Crixivan and Naproxen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Crixivan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Naproxen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Crixivan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Naproxen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on indinavir sulfate and naproxen (the active ingredients of Crixivan and Naproxen, respectively), and Crixivan and Naproxen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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