Flolan and Clonazepam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Flolan (epoprostenol sodium) and Clonazepam (clonazepam). Common drug interactions include menorrhagia among females and aneurysm ruptured among males.

The phase IV clinical study analyzes what interactions people have when they take Flolan and Clonazepam. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Flolan?

Flolan has active ingredients of epoprostenol sodium. eHealthMe is studying from 10,067 Flolan users. Check the latest studies of Flolan.

What is Clonazepam?

Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 146,270 Clonazepam users. Check the latest studies of Clonazepam.

On Jul, 13, 2026

38 people who take Flolan and Clonazepam together, and have interactions are studied.

Flolan and Clonazepam drug interactions.

What are the common drug interactions of Flolan and Clonazepam, by gender? *:

female:

Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Multi-organ failure (multisystem organ failure)
Myalgia (muscle pain)
Oedema peripheral (superficial swelling)
Orthopnoea (shortness of breath (dyspnea) when lying down)
Painful respiration
Palpitations (feelings or sensations that your heart is pounding or racing)
Pericardial effusion (fluid around the heart)
Device related infection
Malaise (a feeling of general discomfort or uneasiness)

male:

Aneurysm ruptured (expansion of the aneurysm reaches a point where the wall becomes too thin, the aneurysm will rupture)
Cerebral haemorrhage (bleeding within the brain)
Dyspnoea (difficult or laboured respiration)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Loss of consciousness
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Oedema lower limb (fluid collection in tissue of lower leg)
Pulmonary embolism (blockage of the main artery of the lung)
Pulmonary hypertension primary (increase in blood pressure in the lung artery with no cause)

What are the common drug interactions of Flolan and Clonazepam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)
Cardiomyopathy (weakening of the heart muscle)
Chest discomfort
Cholecystitis (infection of gallbladder)
Contusion (a type of hematoma of tissue in which capillaries)
Cough
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)

30-39:

Device related infection
Thrombosis (formation of a blood clot inside a blood vessel)
Antiphospholipid syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss)
Cardiac arrest
Cardiac failure congestive
Coagulopathy (blood's ability to clot is impaired)
Diarrhoea
Implant infection (infection at implant site)
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Nausea (feeling of having an urge to vomit)

40-49:

Dizziness
Confusional state
Heart rate increased
Cardioversion
Acute right ventricular failure (acute heart attack)
Arrhythmia (irregular heartbeat)
Blood lactic acid increased
Drug administration error
Malaise (a feeling of general discomfort or uneasiness)
Pneumonia

50-59:

Catheter site infection (infection at the site of insertion)
Cellulitis (infection under the skin)
Chest pain
Device related infection
Diarrhoea
Fatigue (feeling of tiredness)
Feeling hot
Headache (pain in head)
Ill-defined disorder
Infusion site cellulitis

60+:

Pulmonary hypertension (increase in blood pressure in the lung artery)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Insomnia (sleeplessness)
Loss of consciousness
Sleep disorder
Tremor (trembling or shaking movements in one or more parts of your body)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 15 people, 39.47%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 9 people, 23.68%
Cor Pulmonale Chronic (long lasting enlargement of the right ventricle of the heart): 4 people, 10.53%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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