Daptomycin and Valproate sodium drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Daptomycin (daptomycin) and Valproate sodium (valproate sodium). Common drug interactions include pancytopenia among females and oliguria among males.
The phase IV clinical study analyzes what interactions people have when they take Daptomycin and Valproate sodium. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.
What is Daptomycin?
Daptomycin has active ingredients of daptomycin. eHealthMe is studying from 7,879 Daptomycin users. Check the latest studies of Daptomycin.
What is Valproate sodium?
Valproate sodium has active ingredients of valproate sodium. It is often used in epilepsy. eHealthMe is studying from 24,044 Valproate sodium users. Check the latest studies of Valproate sodium.
14 people who take Daptomycin and Valproate sodium together, and have interactions are studied.

What are the common drug interactions of Daptomycin and Valproate Sodium, by gender? *:
female:
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Drug ineffective
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
male:
- Oliguria (not enough urine)
- Myositis (inflammation of the muscles)
- Cerebral haemorrhage (bleeding within the brain)
What are the common drug interactions of Daptomycin and Valproate Sodium, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Oliguria (not enough urine)
10-19:
- Myositis (inflammation of the muscles)
- Cerebral haemorrhage (bleeding within the brain)
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
- Drug ineffective
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
What are the existing conditions these people have? *
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 5 people, 35.71%
- Staphylococcal Infection (an infection with staphylococcus bacteria): 3 people, 21.43%
- Staphylococcal Bacteraemia (a bacterial infection of blood): 2 people, 14.29%
- Pyoderma Gangrenosum (ulcerating condition of skin that results in heaped borders with a typical appearance): 2 people, 14.29%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 14.29%
* Approximation only. Some reports may have incomplete information.
Do you take Daptomycin and Valproate sodium?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Daptomycin (7,879 reports)
- Valproate sodium (24,044 reports)
Browse all drug interactions of Daptomycin and Valproate sodium:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Daptomycin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Valproate sodium:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Daptomycin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Valproate sodium and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Ayano G, "Bipolar Disorders and Valproate: Pharmacokinetics, Pharmacodynamics and Therapeutic Effects and Indications of Valproate: Review of Articles", Bipolar Disord, 2017 Jan .
- Saliho?lu M, Turhan V, ?nem Y, Ulcay A, Uzun G, Ay H, "Sudden hearing loss in a patient receiving piperacillin/tazobactam and daptomycin for diabetic foot infection", Scandinavian journal of infectious diseases, 2013 Mar .
- Bansal S, Gupta SK, "Sodium Valproate induced priapism in an adult with bipolar affective disorder", Indian journal of pharmacology, 2013 Jan .
- Ayano G, "Bipolar Disorders and Valproate: Pharmacokinetics, Pharmacodynamics and Therapeutic Effects and Indications of Valproate: Review of Articles", Bipolar Disord, 2017 Jan .
- Saliho?lu M, Turhan V, ?nem Y, Ulcay A, Uzun G, Ay H, "Sudden hearing loss in a patient receiving piperacillin/tazobactam and daptomycin for diabetic foot infection", Scandinavian journal of infectious diseases, 2013 Mar .
- Bansal S, Gupta SK, "Sodium Valproate induced priapism in an adult with bipolar affective disorder", Indian journal of pharmacology, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on daptomycin and valproate sodium (the active ingredients of Daptomycin and Valproate sodium, respectively), and Daptomycin and Valproate sodium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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