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Daytrana and Metadate cd drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Daytrana (methylphenidate) and Metadate cd (methylphenidate hydrochloride). Common drug interactions include drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Daytrana and Metadate cd. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Daytrana?

Daytrana has active ingredients of methylphenidate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 16,561 Daytrana users. Check the latest studies of Daytrana.

What is Metadate cd?

Metadate cd has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 646 Metadate cd users. Check the latest studies of Metadate cd.

On Jul, 31, 2026

11 people who take Daytrana and Metadate cd together, and have interactions are studied.

Daytrana and Metadate cd drug interactions.

What are the common drug interactions of Daytrana and Metadate Cd, by gender? *:

female:

n/a

male:

  1. Drug ineffective
  2. Drug administration error
  3. Emotional distress
  4. Gynaecomastia (enlargement of the gland tissue of the male breast)
  5. Obesity (having too much body fat)
  6. Application site discolouration
  7. Blood creatine phosphokinase increased
  8. Disturbance in social behaviour
  9. Educational problem
  10. Opisthotonus (a condition in which the body is held in an abnormal position)

What are the common drug interactions of Daytrana and Metadate Cd, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Drug administration error
  2. Gynaecomastia (enlargement of the gland tissue of the male breast)
  3. Obesity (having too much body fat)
  4. Drug ineffective
  5. Blood creatine phosphokinase increased
  6. Disturbance in social behaviour
  7. Educational problem
  8. Opisthotonus (a condition in which the body is held in an abnormal position)
  9. Postoperative wound infection
  10. Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)

10-19:

  1. Disturbance in attention

20-29:

  1. Application site discolouration

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Stress And Anxiety: 2 people, 18.18%
  2. Multiple Allergies (allergy to multiple agents): 2 people, 18.18%
  3. Insomnia (sleeplessness): 2 people, 18.18%
  4. Abnormal Behavior: 2 people, 18.18%
  5. Psychomotor Hyperactivity (feelings of extreme restlessness): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Daytrana and Metadate cd:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Daytrana:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Metadate cd:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Daytrana and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Metadate cd and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on methylphenidate and methylphenidate hydrochloride (the active ingredients of Daytrana and Metadate cd, respectively), and Daytrana and Metadate cd (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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