Ddavp and Acetaminophen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ddavp (desmopressin acetate) and Acetaminophen (acetaminophen). Common drug interactions include ligament sprain among females and hyponatraemia among males.

The phase IV clinical study analyzes what interactions people have when they take Ddavp and Acetaminophen. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Ddavp?

Ddavp has active ingredients of desmopressin acetate. It is often used in diabetes insipidus. eHealthMe is studying from 2,614 Ddavp users. Check the latest studies of Ddavp.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.



On Jul, 04, 2026

44 people who take Ddavp and Acetaminophen together, and have interactions are studied.

Ddavp and Acetaminophen drug interactions.

What are the common drug interactions of Ddavp and Acetaminophen, by gender? *:

female:

  1. Ligament sprain (ligament stretched)
  2. Mobility decreased (ability to move is reduced)
  3. Muscular weakness (muscle weakness)
  4. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  5. Nausea (feeling of having an urge to vomit)
  6. Oedema peripheral (superficial swelling)
  7. Peroneal nerve palsy
  8. Anaemia (lack of blood)
  9. Epigastric discomfort
  10. Hypernatraemia (an abnormally high plasma concentration of sodium ions)

male:

  1. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  2. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  3. White blood cell count decreased
  4. Collapse (sudden functional breakdown)
  5. Dehydration (dryness resulting from the removal of water)
  6. Depressed level of consciousness
  7. Haematoma (collection of blood outside the blood vessels)
  8. Hepatic failure (liver failure)
  9. Hydrocephalus (water on the brain)
  10. Hypernatraemia (an abnormally high plasma concentration of sodium ions)

What are the common drug interactions of Ddavp and Acetaminophen, by age (0-1 to 60+)? *:

0-1:

  1. Decreased appetite
  2. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  3. Myoclonic epilepsy (type of epilepsy with quick little jerks of the arms, shoulder, or occasionally the legs)
  4. Constipation
  5. Muscle spasms (muscle contraction)
  6. Vomiting
  7. Dehydration (dryness resulting from the removal of water)
  8. Hypernatraemia (an abnormally high plasma concentration of sodium ions)
  9. Hypoglycaemia (deficiency of glucose in the bloodstream)
  10. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)

2-9:

n/a

10-19:

  1. Influenza like illness
  2. Electrocardiogram qt prolonged
  3. Electrolyte imbalance
  4. Abdominal tenderness
  5. Nerve compression
  6. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  7. White blood cell count decreased
  8. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  9. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  10. Abdominal pain lower

20-29:

  1. Aortic valve incompetence
  2. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  3. White blood cell count decreased

30-39:

  1. Collapse (sudden functional breakdown)
  2. Depressed level of consciousness
  3. Haematoma (collection of blood outside the blood vessels)
  4. Hydrocephalus (water on the brain)
  5. Respiratory rate increased (excess breathing rate/min)
  6. Brain herniation (brain herniation is a potentially deadly side effect of very high intracranial pressure that occurs when a part of the brain is squeezed across structures within the skull)
  7. Cerebral haemorrhage (bleeding within the brain)
  8. Cerebral infarction (less blood supply to brain resulting tissue damage)
  9. Coma (state of unconsciousness lasting more than six hours)
  10. Craniopharyngioma (a type of brain tumour derived from pituitary gland embryonic tissue)

40-49:

  1. Oral discomfort (pain or irritation in mouth)
  2. Oral disorder (mouth disease)
  3. Osteonecrosis of jaw (death of bone of jaw)
  4. Pain in jaw
  5. Pharyngitis (inflammation of the pharynx, causing a sore throat)
  6. Plasmacytoma (neoplasm of plasma cells (usually in bone marrow))
  7. Pyrexia (fever)
  8. Retinal infarction (retina damage due to less blood supply)
  9. Rhinorrhoea (watery mucus discharge from the nose)
  10. Sinus headache (headache caused by sinus infections)

50-59:

  1. Blood lactic acid increased
  2. Blood thyroid stimulating hormone decreased
  3. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  4. Confusional state
  5. Dehydration (dryness resulting from the removal of water)
  6. Dysarthria (speech disorder)
  7. Dysphagia (a condition in which swallowing is difficult or painful)
  8. Dyspnoea (difficult or laboured respiration)
  9. Epigastric discomfort
  10. Feeling cold

60+:

  1. Blood sodium decreased
  2. Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
  3. Lethargy (tiredness)
  4. Blood creatine phosphokinase increased
  5. Hallucination, visual (seeing things that aren't there)
  6. Pneumonia
  7. Sleep disorder

What are the existing conditions these people have? *

  1. Nausea And Vomiting: 6 people, 13.64%
  2. Agitation (state of anxiety or nervous excitement): 5 people, 11.36%
  3. Fever: 5 people, 11.36%
  4. Lewis-Sumner Syndrome (a dysimmune multifocal demyelinating sensorimotor neuropathy): 4 people, 9.09%
  5. Chronic Inflammatory Demyelinating Polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord): 4 people, 9.09%
  6. Constipation: 4 people, 9.09%
  7. Depression: 4 people, 9.09%
  8. Hypocitraturia (low amount of citrate in the urine, is an important risk factor for kidney stone formation): 4 people, 9.09%
  9. Urine Analysis Abnormal: 4 people, 9.09%
  10. Muscle Aches (muscle pain): 4 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Ddavp and Acetaminophen?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ddavp and Acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ddavp:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ddavp and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Acetaminophen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on desmopressin acetate and acetaminophen (the active ingredients of Ddavp and Acetaminophen, respectively), and Ddavp and Acetaminophen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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