Ddavp and Zoloft drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ddavp (desmopressin acetate) and Zoloft (sertraline hydrochloride). Common drug interactions include gastrointestinal disorder among females and injury among males.

The phase IV clinical study analyzes what interactions people have when they take Ddavp and Zoloft. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.

What is Ddavp?

Ddavp has active ingredients of desmopressin acetate. It is often used in diabetes insipidus. eHealthMe is studying from 2,614 Ddavp users. Check the latest studies of Ddavp.

What is Zoloft?

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 138,798 Zoloft users. Check the latest studies of Zoloft.

On Aug, 10, 2026

54 people who take Ddavp and Zoloft together, and have interactions are studied.

What are the common drug interactions of Ddavp and Zoloft, by gender? *:

female:

Gastrointestinal disorder (functional problems of gastrointestinal tract)
Headache (pain in head)
Herpes zoster
Pain
Abscess (pus)
Acute sinusitis
Alopecia (absence of hair from areas of the body)
Anaemia (lack of blood)
Arthralgia (joint pain)
Blood calcium decreased

male:

Injury
Drug ineffective
Visual impairment
Chills (felling of cold)
Diarrhoea
Pyrexia (fever)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Abnormal behaviour
Diabetes mellitus insulin-dependent
Hypersensitivity

What are the common drug interactions of Ddavp and Zoloft, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Blood glucose increased
Diabetes mellitus insulin-dependent
Drug ineffective
Nausea (feeling of having an urge to vomit)
Urine ketone body present
Alanine aminotransferase increased
Aphasia (damage to the parts of the brain that control language)
Drooling (drop saliva uncontrollably from the mouth)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)

10-19:

Hypersensitivity
Respiratory tract infection
Sinusitis (inflammation of sinus)
Abnormal behaviour
Drug ineffective
Urticaria (rash of round, red welts on the skin that itch intensely)
Weight increased
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Tardive dyskinesia (a disorder that involves involuntary movements)
Aggression

20-29:

Abdominal pain
Acute abdomen
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)

30-39:

Decreased appetite
Fall
Uterine atony (failure of the uterus to contract following delivery)

40-49:

Headache (pain in head)
Herpes zoster
Abscess (pus)
Acute sinusitis
Alopecia (absence of hair from areas of the body)
Anaemia (lack of blood)
Arthralgia (joint pain)
Blood calcium decreased
Bone cyst
Bone disorder

50-59:

Mood altered (changes in mood)
Temporomandibular joint syndrome (pain at the temporomandibular joint due to various causes of increased muscle tension and spasm. it is believed that syndrome is a physical manifestation of psychological stress)
Tendon pain
Tongue injury
Visual impairment
Dyspepsia (indigestion)
Dyspnoea (difficult or laboured respiration)
Pain
Abscess (pus)
Acute sinusitis

60+:

Abdominal pain
Asthenia (weakness)
Diarrhoea
Dysstasia (difficulty in standing)
Malaise (a feeling of general discomfort or uneasiness)
Heart rate increased
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Skin cancer

What are the existing conditions these people have? *

Pain: 6 people, 11.11%
Insomnia (sleeplessness): 6 people, 11.11%
Bipolar Disorder (mood disorder): 6 people, 11.11%
Bedwetting: 6 people, 11.11%
Nausea And Vomiting: 4 people, 7.41%
Nausea (feeling of having an urge to vomit): 4 people, 7.41%
Multiple Myeloma (cancer of the plasma cells): 4 people, 7.41%
Growth Hormone Deficiency: 4 people, 7.41%
Anaemia (lack of blood): 4 people, 7.41%
Stress And Anxiety: 3 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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