Descovy and Clopidogrel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Descovy (emtricitabine; tenofovir alafenamide fumarate) and Clopidogrel (clopidogrel). Common drug interactions include bone pain among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Descovy and Clopidogrel. It is created by eHealthMe based on reports of 64 people who take the same drugs from the FDA, and is updated regularly.

What is Descovy?

Descovy has active ingredients of emtricitabine; tenofovir alafenamide fumarate. It is often used in hiv infection. eHealthMe is studying from 14,260 Descovy users. Check the latest studies of Descovy.

What is Clopidogrel?

Clopidogrel has active ingredients of clopidogrel. It is often used in blood clots. eHealthMe is studying from 92,160 Clopidogrel users. Check the latest studies of Clopidogrel.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

64 people who take Descovy and Clopidogrel together, and have interactions are studied.

Descovy and Clopidogrel drug interactions.

What are the common drug interactions of Descovy and Clopidogrel, by gender? *:

female:

Bone pain
Chronic kidney disease
Cough
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Fracture
Gingival bleeding (bleeding gums)
Hand fracture
Heart rate increased
Multiple fractures
Pruritus (severe itching of the skin)

male:

Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Bone density decreased
Osteoporosis (bones weak and more likely to break)
Abdominal discomfort
Angina pectoris (chest pain due to ischemia of the heart muscle)
Mobility decreased (ability to move is reduced)
Surgery
Renal impairment (severely reduced kidney function)
Urinary tract infection

What are the common drug interactions of Descovy and Clopidogrel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Foot fracture
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteopenia (a condition where bone mineral density is lower than normal)
Renal impairment (severely reduced kidney function)
Rib fracture
Sensory loss (senses loss)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Emotional distress

50-59:

Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Arrhythmia (irregular heartbeat)
Osteoporosis (bones weak and more likely to break)
Asthenia (weakness)
Blood creatinine increased
Bone density decreased
Depression

60+:

Abdominal discomfort
Angina pectoris (chest pain due to ischemia of the heart muscle)
Bone pain
Chronic kidney disease
Death
Gait disturbance
Mobility decreased (ability to move is reduced)
Angioedema (rapid swelling of the dermis)
Diarrhoea
Glomerular filtration rate decreased

What are the existing conditions these people have? *

Insomnia (sleeplessness): 19 people, 29.69%
Stable Angina (a constant chest pain): 13 people, 20.31%
High Blood Pressure: 13 people, 20.31%
Stress And Anxiety: 10 people, 15.62%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 10 people, 15.62%
Diabetes: 9 people, 14.06%
Neuropathy Peripheral (surface nerve damage): 7 people, 10.94%
Hypotension (abnormally low blood pressure): 7 people, 10.94%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 7 people, 10.94%
Cellulitis (infection under the skin): 7 people, 10.94%

* Approximation only. Some reports may have incomplete information.

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