Dexamethasone and Multihance drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dexamethasone (dexamethasone) and Multihance (gadobenate dimeglumine). Common drug interactions include skin fibrosis among females and nephrogenic systemic fibrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Dexamethasone and Multihance. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Dexamethasone?

Dexamethasone has active ingredients of dexamethasone. It is often used in multiple myeloma. eHealthMe is studying from 161,927 Dexamethasone users. Check the latest studies of Dexamethasone.

What is Multihance?

Multihance has active ingredients of gadobenate dimeglumine. eHealthMe is studying from 5,786 Multihance users. Check the latest studies of Multihance.



On Jul, 31, 2026

37 people who take Dexamethasone and Multihance together, and have interactions are studied.

Dexamethasone and Multihance drug interactions.

What are the common drug interactions of Dexamethasone and Multihance, by gender? *:

female:

  1. Skin fibrosis (fibrous tissue formation on skin)
  2. Skin hyperpigmentation (disorders affect the colour of your skin)
  3. Skin lesion
  4. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  5. Oedema peripheral (superficial swelling)
  6. Pain
  7. Skin hypertrophy (skin cells enlarges)
  8. Skin induration (an abnormally hard spot or area on the skin)
  9. Skin tightness
  10. Dry skin

male:

  1. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  2. Mobility decreased (ability to move is reduced)
  3. Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
  4. Rash
  5. Renal disorder (kidney disease)
  6. Skin disorder (skin disease)
  7. Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
  8. Interstitial lung disease
  9. Joint contracture (a permanent shortening of a muscle or joint)
  10. Metaplasia (change in the type of adult cells in a tissue to a form abnormal for that tissue)

What are the common drug interactions of Dexamethasone and Multihance, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Muscle contracture (a permanent shortening of a muscle)
  2. Skin fibrosis (fibrous tissue formation on skin)
  3. Discomfort
  4. Pain
  5. Cardiac valve disease (heart valve disease)
  6. Extremity contracture (permanent shortening of a muscle or joint of arms and legs)
  7. Nephrogenic fibrosing dermopathy (involves fibrosis of skin, joints, eyes due to kidney disease)
  8. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  9. Cardiac arrest
  10. Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)

20-29:

n/a

30-39:

n/a

40-49:

  1. Arthralgia (joint pain)
  2. Asthenia (weakness)
  3. Chronic kidney disease
  4. Deformity (disfigurement)
  5. Erythema (redness of the skin)
  6. Exfoliative rash (scaly red generalized skin rash)
  7. Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
  8. Gait disturbance
  9. General physical health deterioration (weak health status)
  10. Joint contracture (a permanent shortening of a muscle or joint)

50-59:

  1. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  2. Pain
  3. Dry skin
  4. Erythema (redness of the skin)
  5. Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
  6. Hyperkeratosis (thickening of the outer layer of the skin)
  7. Impaired healing
  8. Mobility decreased (ability to move is reduced)
  9. Muscular weakness (muscle weakness)
  10. Oedema (fluid collection in tissue)

60+:

  1. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
  2. Oedema peripheral (superficial swelling)
  3. Skin induration (an abnormally hard spot or area on the skin)
  4. Skin plaque (red, scaly patches to appear on the skin)
  5. Interstitial lung disease
  6. Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
  7. Injection site bruising
  8. Injection site erythema (redness at injection site)
  9. Injection site pain
  10. Injection site pruritus (severe itching at injection site)

What are the existing conditions these people have? *

  1. Nuclear Magnetic Resonance Imaging Brain: 13 people, 35.14%
  2. Joint Pain: 9 people, 24.32%
  3. Nuclear Magnetic Resonance Imaging Abdominal: 8 people, 21.62%
  4. Catheter Related Complication: 8 people, 21.62%
  5. Weakness: 7 people, 18.92%
  6. Dizziness: 7 people, 18.92%
  7. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 6 people, 16.22%
  8. Anaemia (lack of blood): 5 people, 13.51%
  9. Renal Osteodystrophy (a bone disease occurs when the kidneys fail to maintain the proper levels of calcium and phosphorus in the blood): 3 people, 8.11%
  10. Hypercalcaemia (elevated calcium (ca+) level in the blood): 3 people, 8.11%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Dexamethasone and Multihance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Dexamethasone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Multihance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Dexamethasone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Multihance and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on dexamethasone and gadobenate dimeglumine (the active ingredients of Dexamethasone and Multihance, respectively), and Dexamethasone and Multihance (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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