Dexchlorpheniramine maleate and Bactrim drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Dexchlorpheniramine maleate (dexchlorpheniramine maleate) and Bactrim (sulfamethoxazole; trimethoprim). Common drug interactions include hyperlipidaemia among females and infusion related reaction among males.

The phase IV clinical study analyzes what interactions people have when they take Dexchlorpheniramine maleate and Bactrim. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Dexchlorpheniramine maleate?

Dexchlorpheniramine maleate has active ingredients of dexchlorpheniramine maleate. eHealthMe is studying from 1,509 Dexchlorpheniramine maleate users. Check the latest studies of Dexchlorpheniramine maleate.

What is Bactrim?

Bactrim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 89,117 Bactrim users. Check the latest studies of Bactrim.

On Jul, 21, 2026

57 people who take Dexchlorpheniramine maleate and Bactrim together, and have interactions are studied.

Dexchlorpheniramine maleate and Bactrim drug interactions.

What are the common drug interactions of Dexchlorpheniramine Maleate and Bactrim, by gender? *:

female:

Hyperlipidaemia (presence of excess lipids in the blood)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypokalaemia (low potassium)
Immune reconstitution syndrome (immune recovery syndrome)
Lactic acidosis (low ph in body tissues)
Lipodystrophy acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
Oedema (fluid collection in tissue)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)

male:

Infusion related reaction
Dyspnoea (difficult or laboured respiration)
Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
Urticaria (rash of round, red welts on the skin that itch intensely)
C-reactive protein increased
Cardiac failure
Cardiac valve disease (heart valve disease)
Feeling hot
Flushing (the warm, red condition of human skin)
Hypotension (abnormally low blood pressure)

What are the common drug interactions of Dexchlorpheniramine Maleate and Bactrim, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)
Leukopenia (less number of white blood cells in blood)
Sepsis (a severe blood infection that can lead to organ failure and death)

10-19:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Diarrhoea
Febrile neutropenia (fever with reduced white blood cells)
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
Septic shock (shock due to blood infection)

20-29:

Conjunctivitis (pink eye)
Cystitis haemorrhagic (blood in the urine and painful voiding)
Drug ineffective
Electrocardiogram qt corrected interval prolonged
Electrocardiogram qt prolonged
Fungal sepsis (whole body infection by fungus)
Hypokalaemia (low potassium)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
Oedema (fluid collection in tissue)

30-39:

Pulmonary hypertension (increase in blood pressure in the lung artery)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Drug hypersensitivity
Dyskinesia (abnormality or impairment of voluntary movement)
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Pyrexia (fever)

40-49:

Blood lactic acid increased
Breast enlargement
Dry skin
Dyspnoea exertional (breathlessness or shortness of breath)
Gammopathy (abnormal proliferation of the lymphoid cells producing immunoglobulins)
Gastritis (inflammation of stomach)
Hepatomegaly (abnormal enlargement of the liver)
Hirsutism (abnormal growth of hair on a person's face and body, esp. on a woman)
Hypercholesterolaemia (high levels of cholesterol in the blood)
Hyperlipidaemia (presence of excess lipids in the blood)

50-59:

Abdominal pain
Decreased appetite
Nausea (feeling of having an urge to vomit)
Vomiting
Dyspnoea (difficult or laboured respiration)
Drug hypersensitivity
Infusion related reaction
Feeling hot
Flushing (the warm, red condition of human skin)
Hypotension (abnormally low blood pressure)

60+:

Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Aspartate aminotransferase increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
C-reactive protein increased
Cardiac disorder
Cardiac failure
Cardiac valve disease (heart valve disease)
Febrile neutropenia (fever with reduced white blood cells)
Multi-organ failure (multisystem organ failure)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 7 people, 12.28%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 6 people, 10.53%
Hiv Infection: 5 people, 8.77%
Burkitt Lymphoma (cancer of the lymphatic system): 5 people, 8.77%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 5 people, 8.77%
Waldenstrom's Macroglobulinaemia (cancer affects small lymphocytes (white blood cells)): 3 people, 5.26%
Aplastic Anemia: 3 people, 5.26%
Adverse Event: 3 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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