Diazepam and Bosentan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diazepam (diazepam) and Bosentan (bosentan). Common drug interactions include ankle fracture among females and pulmonary hypertension among males.

The phase IV clinical study analyzes what interactions people have when they take Diazepam and Bosentan. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Diazepam?

Diazepam has active ingredients of diazepam. It is often used in stress and anxiety. eHealthMe is studying from 108,384 Diazepam users. Check the latest studies of Diazepam.

What is Bosentan?

Bosentan has active ingredients of bosentan. eHealthMe is studying from 10,925 Bosentan users. Check the latest studies of Bosentan.

On Jul, 13, 2026

24 people who take Diazepam and Bosentan together, and have interactions are studied.

Diazepam and Bosentan drug interactions.

What are the common drug interactions of Diazepam and Bosentan, by gender? *:

female:

Ankle fracture
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Fall
Oxygen saturation decreased
Red blood cell count decreased
Respiratory syncytial virus infection (viral disease of respiratory system)
Thrombosis (formation of a blood clot inside a blood vessel)
Accidental poisoning
Acute respiratory failure

male:

Pulmonary hypertension (increase in blood pressure in the lung artery)
Acute respiratory failure
Tracheostomy malfunction (a surgical opening of trachea not working normally)
Vomiting
Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis)
Cardiac disorder
Cough
Decreased appetite
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Gastric ph decreased

What are the common drug interactions of Diazepam and Bosentan, by age (0-1 to 60+)? *:

0-1:

Acute respiratory failure
Catheter site discharge
Catheter site haemorrhage (bleeding at catheter site)
Catheter site pain
Catheter site swelling
Feeling hot
Flushing (the warm, red condition of human skin)
Infusion site pain
Pyrexia (fever)
Tracheostomy malfunction (a surgical opening of trachea not working normally)

2-9:

Acute respiratory failure
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Disease complication
Lung disorder (lung disease)
Nausea (feeling of having an urge to vomit)
Pneumonia klebsiella (pneumonia caused by bacteria klebsiella)
Pneumonia staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus)
Trisomy 18 (a genetic disorder caused by the presence of all or part of an extra 18th chromosome)
Vomiting
Hospitalisation

10-19:

Cardiac disorder
Decreased appetite
Gastric ph decreased
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Hospitalisation
Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)

20-29:

n/a

30-39:

Abdominal pain upper
Haematemesis (vomiting of blood)

40-49:

n/a

50-59:

Accidental poisoning
Headache (pain in head)
Pain in extremity
Vision blurred
Chronic kidney disease
Death
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Anaemia of chronic disease
Drug hypersensitivity

60+:

Ankle fracture
Dehydration (dryness resulting from the removal of water)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Hypersomnia (excessive daytime sleepiness (eds))
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Iron deficiency anaemia
Lumbar vertebral fracture
Diarrhoea
Fall
Oxygen saturation decreased

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 11 people, 45.83%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 6 people, 25.00%
Osteoporosis (bones weak and more likely to break): 5 people, 20.83%
Nausea (feeling of having an urge to vomit): 3 people, 12.50%
Eye Disorder: 3 people, 12.50%
Urination - Excessive Volume: 2 people, 8.33%
Pain: 2 people, 8.33%
Oxygen Consumption Decreased: 2 people, 8.33%
Neuralgia (pain in one or more nerves): 2 people, 8.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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