Diclofenac and Simbrinza drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Diclofenac (diclofenac) and Simbrinza (brimonidine tartrate; brinzolamide). Common drug interactions include abnormal sleep-related event among females and rectal haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Diclofenac and Simbrinza. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Diclofenac?

Diclofenac has active ingredients of diclofenac. eHealthMe is studying from 41,319 Diclofenac users. Check the latest studies of Diclofenac.

What is Simbrinza?

Simbrinza has active ingredients of brimonidine tartrate; brinzolamide. It is often used in glaucoma. eHealthMe is studying from 4,543 Simbrinza users. Check the latest studies of Simbrinza.

On Jul, 19, 2026

12 people who take Diclofenac and Simbrinza together, and have interactions are studied.

Diclofenac and Simbrinza drug interactions.

What are the common drug interactions of Diclofenac and Simbrinza, by gender? *:

female:

Abnormal sleep-related event
Blood potassium decreased
Blood pressure fluctuation
Cardiac arrest
Cataract (clouding of the lens inside the eye)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Chronic kidney disease
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dizziness

male:

Rectal haemorrhage (bleeding from anus)
Abdominal discomfort
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Dysstasia (difficulty in standing)
Epistaxis (bleed from the nose)
Eye pain
Fatigue (feeling of tiredness)
Fear
Flatulence (flatus expelled through the anus)

What are the common drug interactions of Diclofenac and Simbrinza, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Dysstasia (difficulty in standing)
Epistaxis (bleed from the nose)
Eye pain
Fatigue (feeling of tiredness)
Fear
Flatulence (flatus expelled through the anus)
Gout (uric acid crystals building up in the body)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Head injury
Headache (pain in head)

60+:

Dyspnoea (difficult or laboured respiration)
Rectal haemorrhage (bleeding from anus)
Bladder pain
Blood potassium decreased
Blood pressure fluctuation
Blood urine present
Cardiac arrest
Cataract (clouding of the lens inside the eye)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Choking (mechanical obstruction of the flow of air from the environment into the lungs)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 3 people, 25.00%
Sleep Disorder: 2 people, 16.67%
Diarrhea: 2 people, 16.67%
Pain: 2 people, 16.67%
Oral Herpes (viral infection of mouth): 2 people, 16.67%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 16.67%
Back Pain: 1 person, 8.33%
Blood Pressure Abnormal: 1 person, 8.33%
Bone Disorder: 1 person, 8.33%
Cardiac Disorder: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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