Digoxin and Canagliflozin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Digoxin (digoxin) and Canagliflozin (canagliflozin). Common drug interactions include chest pain among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Digoxin and Canagliflozin. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Digoxin?

Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.

What is Canagliflozin?

Canagliflozin has active ingredients of canagliflozin. eHealthMe is studying from 3,253 Canagliflozin users. Check the latest studies of Canagliflozin.

On Jul, 15, 2026

26 people who take Digoxin and Canagliflozin together, and have interactions are studied.

Digoxin and Canagliflozin drug interactions.

What are the common drug interactions of Digoxin and Canagliflozin, by gender? *:

female:

Chest pain
Dizziness
Fatigue (feeling of tiredness)
Palpitations (feelings or sensations that your heart is pounding or racing)
Rhinorrhoea (watery mucus discharge from the nose)
Abdominal discomfort
Chest discomfort
Cystitis (inflammation of the wall of the bladder)
Decreased appetite
Diarrhoea

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hyperglycaemia (high blood sugar)
Localised infection (infection at the single location)
Pneumonia
Sepsis (a severe blood infection that can lead to organ failure and death)
Renal injury (kidney injury)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

What are the common drug interactions of Digoxin and Canagliflozin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Hypovolaemia (a decreased volume of circulating blood in the body)

40-49:

n/a

50-59:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Nephropathy (damage to or disease of a kidney)
Cardiac failure
Cardiomyopathy (weakening of the heart muscle)
Fluid overload (too much fluid in the blood)
Post procedural complication

60+:

Chest pain
Dizziness
Depressed mood
Diarrhoea
Dysphonia (speech disorder attributable to a disorder of phonation)
Dyspnoea exertional (breathlessness or shortness of breath)
Faeces discoloured
Nausea (feeling of having an urge to vomit)
Productive cough
Pyrexia (fever)

What are the existing conditions these people have? *

Pain: 8 people, 30.77%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 30.77%
Diabetes: 8 people, 30.77%
High Blood Pressure: 7 people, 26.92%
High Blood Cholesterol: 7 people, 26.92%
Oedema (fluid collection in tissue): 6 people, 23.08%
Iron Deficiency: 6 people, 23.08%
Cough: 6 people, 23.08%
Cardiomyopathy (weakening of the heart muscle): 6 people, 23.08%
Cardiac Failure Congestive: 6 people, 23.08%

* Approximation only. Some reports may have incomplete information.

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