Digoxin and Cefazolin sodium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Digoxin (digoxin) and Cefazolin sodium (cefazolin sodium). Common drug interactions include haematoma among females and cardiac arrest among males.

The phase IV clinical study analyzes what interactions people have when they take Digoxin and Cefazolin sodium. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Digoxin?

Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.

What is Cefazolin sodium?

Cefazolin sodium has active ingredients of cefazolin sodium. eHealthMe is studying from 3,649 Cefazolin sodium users. Check the latest studies of Cefazolin sodium.



On Jul, 27, 2026

34 people who take Digoxin and Cefazolin sodium together, and have interactions are studied.

Digoxin and Cefazolin sodium drug interactions.

What are the common drug interactions of Digoxin and Cefazolin Sodium, by gender? *:

female:

  1. Haematoma (collection of blood outside the blood vessels)
  2. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  3. Hypotension (abnormally low blood pressure)
  4. Interstitial pneumonia (lung disease characterized by progressive scarring of both lungs)
  5. Lung transplant
  6. Lung transplant rejection (failure of lung transplant)
  7. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
  8. Multi-organ failure (multisystem organ failure)
  9. Nasopharyngitis (inflammation of the nasopharynx)
  10. Palpitations (feelings or sensations that your heart is pounding or racing)

male:

  1. Cardiac arrest
  2. Blood parathyroid hormone increased
  3. Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
  4. Lung neoplasm malignant (cancer tumour of lung)
  5. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  6. Pain
  7. Pneumonia
  8. Pneumonitis aspiration (acute lung injury after the inhalation of regurgitated gastric contents)
  9. Post procedural infection
  10. Pulmonary embolism (blockage of the main artery of the lung)

What are the common drug interactions of Digoxin and Cefazolin Sodium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Bronchitis acute (acute inflammation of the mucous membrane in the bronchial tubes)
  2. Pneumonia
  3. Thrombocytopenia (decrease of platelets in blood)
  4. Upper respiratory tract infection
  5. Urinary tract infection

10-19:

n/a

20-29:

  1. Antinuclear factor positive
  2. Drug hypersensitivity
  3. Interstitial pneumonia (lung disease characterized by progressive scarring of both lungs)
  4. Lung transplant
  5. Lung transplant rejection (failure of lung transplant)
  6. Respiratory disorder (respiratory disease)

30-39:

  1. Device related infection
  2. Cardioversion
  3. Anaemia (lack of blood)
  4. Alanine aminotransferase increased
  5. Aspartate aminotransferase increased
  6. Cardiac failure
  7. Catheter related infection
  8. Gamma-glutamyltransferase increased
  9. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  10. Nasopharyngitis (inflammation of the nasopharynx)

40-49:

n/a

50-59:

  1. Angina pectoris (chest pain due to ischemia of the heart muscle)
  2. Arthralgia (joint pain)
  3. Asthenia (weakness)
  4. Back pain
  5. Cardiac arrest
  6. Cardioactive drug level increased
  7. Chest discomfort
  8. Chest pain
  9. Confusional state
  10. Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)

60+:

  1. Bradycardia (abnormally slow heart action)
  2. Cardiac arrest
  3. Red blood cell count decreased
  4. Respiratory failure (inadequate gas exchange by the respiratory system)
  5. Sepsis (a severe blood infection that can lead to organ failure and death)
  6. Staphylococcal infection (an infection with staphylococcus bacteria)
  7. Thrombocytopenia (decrease of platelets in blood)
  8. Cardiac failure
  9. Cardiac failure chronic
  10. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)

What are the existing conditions these people have? *

  1. Right Ventricular Failure (right half of the heart fails to work): 5 people, 14.71%
  2. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 5 people, 14.71%
  3. Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 4 people, 11.76%
  4. Anaesthesia: 4 people, 11.76%
  5. Hypokalemia (low potassium): 3 people, 8.82%
  6. Device Related Infection: 3 people, 8.82%
  7. Pain: 2 people, 5.88%
  8. Hypotonia (low muscle tone): 2 people, 5.88%
  9. High Blood Pressure: 2 people, 5.88%
  10. Cardioversion: 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Digoxin and Cefazolin sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Digoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cefazolin sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Digoxin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cefazolin sodium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on digoxin and cefazolin sodium (the active ingredients of Digoxin and Cefazolin sodium, respectively), and Digoxin and Cefazolin sodium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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